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多重微生物菌血症和类圆线虫超感染综合征:对使用皮质类固醇激素患者的警惕

Polymicrobial bacteremia and Strongyloides hyperinfection syndrome: Vigilance in patients on corticosteroids.

作者信息

Boyle Evan, Coppock Dagan

机构信息

Thomas Jefferson University Hospital, Division of Infectious Diseases, United States.

出版信息

IDCases. 2022 May 20;28:e01520. doi: 10.1016/j.idcr.2022.e01520. eCollection 2022.

Abstract

Strongyloidiasis is a worldwide parasitic infection. Many who develop infection remain asymptomatic. Due to Stronygloides autoinfection cycle it can result in chronic infection over decades. Immunosuppression particularly with corticosteroids has been associated with a rapid acceleration of the autoinfection cycle known as Strongyloides hyperinfection syndrome. The hyperinfection syndrome has severe complications and is associated with significant patient mortality. Here we report a case of hyperinfection complicated by polymicrobial bacteremia and intestinal ileus and review the literature regarding the hyperinfection syndrome.

摘要

类圆线虫病是一种全球性的寄生虫感染。许多感染者并无症状。由于类圆线虫的自身感染循环,它可导致数十年的慢性感染。免疫抑制,尤其是使用皮质类固醇,与被称为类圆线虫超感染综合征的自身感染循环快速加速有关。超感染综合征有严重并发症,且与患者的高死亡率相关。在此,我们报告一例并发多微生物菌血症和肠梗阻的超感染病例,并回顾有关超感染综合征的文献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a1ff/9125627/dd6d96ca0064/gr1.jpg

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