Department of Interventional Treatment, First Hospital of Qinhuangdao, Qinhuangdao, Hebei Province, P. R. China.
Minim Invasive Ther Allied Technol. 2022 Oct;31(7):1096-1102. doi: 10.1080/13645706.2022.2079381. Epub 2022 May 26.
To evaluate the feasibility and safety of percutaneous transluminal forceps biopsy (PTFB) with an adjustable curved sheath in patients with obstructive jaundice.
Forty-two patients who underwent PTFB with an adjustable curved sheath were analyzed retrospectively. Sensitivity, specificity, negative predictive value (NPV), positive predictive value (PPV) and accuracy were calculated for all populations and in different situations. Technical success and safety were evaluated.
The technical success rate was 100%. Thirty-five of 42 cases were diagnosed malignant diseases, the sensitivity of PTFB with an adjustable curved sheath was 74.29% (26/35), the specificity was 100%, the positive predictive value was 100%, the negative predictive value was 43.75% (7/16), and the accuracy rate was 78.57% (33/42). There was a better sensitivity for bile duct malignancies when compared with non-bile duct malignancies ( = 0.012). No statistical difference was found in the sensitivity of the upper part of the biliary tree and the lower part of the biliary tree, and none in the sensitivity of different approaches (left vs. right). The complication rate was 11.90%, and no serious complications were observed.
PTFB with an adjustable curved sheath is an effective and safe technique, without being limited by approaches and obstruction sites.
评估可调弯鞘经皮经肝胆道钳取活检术（PTFB）在梗阻性黄疸患者中的可行性和安全性。
回顾性分析了 42 例行可调弯鞘 PTFB 的患者。对所有人群和不同情况下的敏感性、特异性、阴性预测值（NPV）、阳性预测值（PPV）和准确性进行了计算。评估了技术成功率和安全性。
技术成功率为 100%。42 例中有 35 例诊断为恶性疾病，可调弯鞘 PTFB 的敏感性为 74.29%（26/35），特异性为 100%，阳性预测值为 100%，阴性预测值为 43.75%（7/16），准确率为 78.57%（33/42）。胆管恶性肿瘤的敏感性明显优于非胆管恶性肿瘤（P=0.012）。胆道树上部和下部、不同入路（左侧与右侧）之间的敏感性均无统计学差异。并发症发生率为 11.90%，无严重并发症。
可调弯鞘 PTFB 是一种有效且安全的技术，不受入路和梗阻部位的限制。
