de Pedro J
Neuroepidemiology. 1986;5(4):207-19. doi: 10.1159/000110830.
The prevalence of parkinsonism varies severalfold between different countries in the world. This could be due to an accumulation of risk factors in certain areas. In the present paper we have analyzed the regional distribution of parkinsonism in Sweden in order to see if such areas could be found within one country. The study was based on sales of levodopa in the different counties of Sweden, and the results were standardized for age and quality of health services as indicated by the local infant mortality rates. The mean prevalence of the different Swedish counties was estimated to be in the middle range of known prevalences. There was a 60% variation within Sweden between the different counties, but the regional distribution did not show a systematic pattern. Further analysis of the causes for this variation showed that differences in case ascertainment and in drug policy could well account for the observed regional differences in parkinsonism prevalence.
帕金森症的患病率在世界不同国家之间相差数倍。这可能是由于某些地区风险因素的累积。在本文中，我们分析了瑞典帕金森症的区域分布情况，以确定在一个国家内是否能找到此类地区。该研究基于瑞典不同郡县左旋多巴的销售情况，并根据当地婴儿死亡率所反映的年龄和卫生服务质量对结果进行了标准化处理。瑞典不同郡县的平均患病率估计处于已知患病率的中等范围。瑞典不同郡县之间存在60%的差异，但区域分布并未呈现出系统模式。对这种差异原因的进一步分析表明，病例确诊和药物政策的差异很可能解释了观察到的帕金森症患病率的区域差异。
