Galea Olivia, O'Leary Shaun, Treleaven Julia
Neck and Head Research Unit, School of Health and Rehabilitation Sciences, University of Queensland, Brisbane, Australia (Drs Galea, O'Leary, and Treleaven); and Physiotherapy Department, Royal Brisbane and Women's Hospital, Brisbane, Australia (Dr O'Leary).
J Head Trauma Rehabil. 2023;38(1):E79-E87. doi: 10.1097/HTR.0000000000000783. Epub 2022 May 26.
The Buffalo Concussion Treadmill Test (BCTT) was developed to identify potential physiological system impairment (PSI) underlying persistent symptoms post-mild traumatic brain injury (mTBI). This study evaluates PSI in individuals 4 weeks to 6 months post-mTBI using the BCTT "failure" criteria, and additional exploratory measures of test duration and heart rate (HR) response.
Tertiary hospital and university.
Participants included 73 individuals 4 weeks to 6 months post-mTBI and a comparison group of 39 healthy controls (HCs). The mTBI group was further subgrouped at screening into those considering themselves asymptomatic (Asymp mTBI) ( n = 35) or symptomatic (Symp mTBI) ( n = 36).
Observational cohort study.
BCTT; failure rate (%), test duration (minutes), HR responses.
: Thirty percent of the mTBI group (including 50% of the Symp and 9% of the Asymp subgroups) failed the BCTT. BCTT duration and associated overall HR change was significantly lower in the mTBI group and Symp subgroup compared with HCs. Compared with HCs maximal HR percentage was higher for the first 4 minutes of the test in the mTBI group, and for the first 2 minutes of the test for the Symp subgroup.
Individuals post-mTBI demonstrated PSI impairment subacutely. In some individuals this was despite an initially reported absence of symptoms. The study also showed some preliminary evidence that BCTT duration and HR responses may be additionally informative post-mTBI.
水牛城脑震荡跑步机测试（BCTT）旨在识别轻度创伤性脑损伤（mTBI）后持续症状背后的潜在生理系统损害（PSI）。本研究使用BCTT“失败”标准以及测试持续时间和心率（HR）反应的额外探索性指标，评估mTBI后4周至6个月个体的PSI。
三级医院和大学。
参与者包括73名mTBI后4周至6个月的个体以及39名健康对照（HC）的比较组。mTBI组在筛查时进一步细分为自认为无症状（无症状mTBI）（n = 35）或有症状（有症状mTBI）（n = 36）的个体。
观察性队列研究。
BCTT；失败率（%）、测试持续时间（分钟）、HR反应。
mTBI组中有30%（包括有症状亚组的50%和无症状亚组的9%）未通过BCTT。与HC相比，mTBI组和有症状亚组的BCTT持续时间及相关的总体HR变化显著更低。与HC相比，mTBI组在测试的前4分钟以及有症状亚组在测试的前2分钟的最大HR百分比更高。
mTBI后的个体在亚急性期表现出PSI损害。在一些个体中，尽管最初报告无症状，但仍存在这种情况。该研究还显示了一些初步证据，表明BCTT持续时间和HR反应在mTBI后可能具有额外的信息价值。
