大鼠肠糖蛋白对³²P标记的大肠杆菌补体溶解活性的影响
Effect of rat intestinal glycoprotein on complement lytic activity of 32P-labelled Escherichia coli.
作者信息
Winsnes R, Midtvedt T, Mellbye O J
出版信息
Scand J Immunol. 1978;7(6):467-72. doi: 10.1111/j.1365-3083.1978.tb00479.x.
Evidence for complement activation by an intestinal glycoprotein fraction from germfree rats is presented. The lowering effect on human serum bactericidal activity of E. coli was 28% for the intestinal glycoprotein fraction, 31% for zymosan, and 25% for inulin, while the lowering effect on conventional rat serum bactericidal activity was 65%, 53% and 21%, respectively. 32P-releasing activity of serum from germfree rats and from man on labelled E. coli amounted to 8% and 28%, respectively, of the release exerted by serum from conventional rats.
本文展示了无菌大鼠肠道糖蛋白组分激活补体的证据。肠道糖蛋白组分对人血清抗大肠杆菌杀菌活性的降低作用为28%，酵母聚糖为31%，菊粉为25%；而对常规大鼠血清杀菌活性的降低作用分别为65%、53%和21%。无菌大鼠和人的血清对标记大肠杆菌的³²P释放活性分别为常规大鼠血清释放量的8%和28%。
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