Reinecke M
Neurosci Lett. 1987 Jan 27;73(3):220-4. doi: 10.1016/0304-3940(87)90248-5.
With the use of different region-specific antisera and the peroxidase-antiperoxidase (PAP) technique, neurotensin-immunoreactivity was found in nerve fibers of the human fallopian tube. Neurotensin-immunoreactive fibers occurred at blood vessels and in contact with smooth muscle cells of the muscular stratum. In vitro experiments with helical strips of the myometrium revealed dose-dependent excitatory actions of neurotensin on resting tension as well as on amplitude and frequency of spontaneous contractions. The results may suggest a neurotransmitter function of neurotensin in the regulation of human oviductal smooth muscle activity. Thus, neurotensin may be essential in the transport of the eggs through the fallopian tube.
利用不同的区域特异性抗血清和过氧化物酶-抗过氧化物酶（PAP）技术，在人输卵管的神经纤维中发现了神经降压素免疫反应性。神经降压素免疫反应性纤维出现在血管处，并与肌层的平滑肌细胞接触。对子宫肌层螺旋条带的体外实验表明，神经降压素对静息张力以及自发收缩的幅度和频率具有剂量依赖性兴奋作用。这些结果可能提示神经降压素在调节人输卵管平滑肌活动中具有神经递质功能。因此，神经降压素可能在卵子通过输卵管的运输过程中起重要作用。
