From the Departments of Nuclear Medicine.
Diagnostic Pathology and Laboratory Medicine.
Clin Nucl Med. 2022 Dec 1;47(12):e762-e764. doi: 10.1097/RLU.0000000000004302. Epub 2022 May 27.
Somatostatin receptor scintigraphy with 99m Tc-Tektrotyd is widely used for the investigation of neuroendocrine tumors. Overexpression of somatostatin receptors has been shown in different tumor types including lymphomas, breast carcinoma, and renal cell carcinoma (RCC). Isolated case reports have shown that RCC metastases can be identified using somatostatin receptor imaging such as Octreoscan scintigraphy and 68 Ga-DOTATATE PET/CT. We report the case of a 70-year-old man with a history of surgically removed RCC who referred to 99m Tc-Tektrotyd scintigraphy for the evaluation of a pancreatic tail lesion. The scan revealed intense tracer uptake in a left splenius cervicis muscle lesion that on biopsy was consistent with metastatic RCC.
99mTc-Tektrotyd 生长抑素受体闪烁显像术被广泛用于神经内分泌肿瘤的研究。不同类型的肿瘤中均显示出生长抑素受体的过度表达，包括淋巴瘤、乳腺癌和肾细胞癌（RCC）。个案报道显示，使用生长抑素受体显像，如奥曲肽闪烁显像和 68Ga-DOTATATE PET/CT，可识别 RCC 转移灶。我们报告了一例 70 岁男性患者的病例，该患者曾接受过 RCC 切除术，因胰腺尾部病变而行 99mTc-Tektrotyd 闪烁显像术检查。扫描显示左颈多裂肌病变部位有强烈的示踪剂摄取，活检结果与转移性 RCC 一致。
