Cruz Megan A, Morris Daniel L, Swanson John P, Kundu Mangaldeep, Mankoci Steven G, Leeper Thomas C, Joy Abraham
Department of Polymer Science, The University of Akron, Akron, Ohio 44325, United States.
Department of Chemistry and Biochemistry, The University of Akron, Akron, Ohio 44325, United States.
ACS Macro Lett. 2018 Apr 17;7(4):477-481. doi: 10.1021/acsmacrolett.8b00118. Epub 2018 Mar 27.
Presented here is a novel method for encapsulating proteins into biodegradable, thermoresponsive coacervate-type polyesters. Bovine serum albumin (BSA) was efficiently incorporated into coacervate droplets via a simple thermoresponsive encapsulation mechanism. Tunable modular systems for encapsulation such as the one presented here may be useful in a range of protein delivery applications.
本文介绍了一种将蛋白质封装到可生物降解的、热响应性凝聚型聚酯中的新方法。牛血清白蛋白（BSA）通过一种简单的热响应封装机制被有效地包裹在凝聚液滴中。像本文所介绍的这种可调谐模块化封装系统可能在一系列蛋白质递送应用中有用。
