Driban Matthew, Chhablani Jay
Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Graefes Arch Clin Exp Ophthalmol. 2022 Nov;260(11):3465-3469. doi: 10.1007/s00417-022-05708-4. Epub 2022 May 27.
To analyze the typical presentation of acute posterior vitreous detachment (PVD), including demographics and prevalence of various treatable findings in the same and fellow eye.
Retrospective analysis of medical records from 2346 patients with acute PVD. Descriptive statistics were generated on age, sex, contact date, visual acuity, and slit lamp, and fundoscopy findings. Multivariate regressions were used to generate odds ratios with 95% confidence intervals (CI) to quantify associations between variables.
A total of 4692 eyes from 2346 patients were analyzed. Most patients were female (60.5%) with an average age of 62.8 years old. Overall, 605 patients (25.8%) had any additional ocular finding on fundus exam, including pigmentation (N = 184, 7.8%), lattice degeneration (N = 158, 6.7%), tear (N = 131, 5.6%), and hole (N = 131, 5.2%). Unilateral retinal detachment was present in 26 patients (1.1%), and these patients demonstrated a similar rate (26.9%) of additional ocular findings compared to the entire sample size. Female sex (OR 1.21, 95% CI 1.03-1.43, p = 0.020) was independently associated with presentation during spring or summer.
Acute PVD is associated with a number of risk factors and peripheral lesions. These findings may be useful in treating and predicting the course and development of PVD.
分析急性玻璃体后脱离（PVD）的典型表现，包括患者的人口统计学特征以及同一眼和对侧眼中各种可治疗病变的发生率。
对2346例急性PVD患者的病历进行回顾性分析。对年龄、性别、就诊日期、视力、裂隙灯检查和眼底检查结果进行描述性统计。采用多因素回归分析生成比值比及95%置信区间（CI），以量化各变量之间的关联。
共分析了2346例患者的4692只眼。大多数患者为女性（60.5%），平均年龄62.8岁。总体而言，605例患者（25.8%）在眼底检查时有其他眼部病变，包括色素沉着（n = 184，7.8%）、格子样变性（n = 158，6.7%）、裂孔（n = 131，5.6%）和视网膜裂孔（n = 131，5.2%）。26例患者（1.1%）出现单侧视网膜脱离，与整个样本相比，这些患者的其他眼部病变发生率相似（26.9%）。女性（比值比1.21，95%CI 1.03 - 1.43，p = 0.020）与春季或夏季发病独立相关。
急性PVD与多种危险因素及周边病变相关。这些发现可能有助于PVD的治疗及病程和发展的预测。
