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胃癌术后患者对口服营养补充治疗的偏好:离散选择实验。

Preferences for oral nutritional supplement therapy among postoperative patients with gastric cancer: a discrete choice experiment.

机构信息

Department of Fundamental Nursing, School of Nursing, Jilin University, Changchun, 130021, Jilin Province, People's Republic of China.

Department of Histology and Embryology, College of Basic Medical Sciences, Jilin University, Changchun, 130021, Jilin Province, People's Republic of China.

出版信息

Support Care Cancer. 2022 Sep;30(9):7447-7456. doi: 10.1007/s00520-022-07154-8. Epub 2022 May 27.

Abstract

PURPOSES

Patients after gastrectomy have poor compliance with oral nutritional supplement (ONS) therapy. Incorporating patient preferences into treatment decisions allows possible product improvements or treatment focus adjustments. The purpose of this research was to investigate the preferences for ONS therapy among postoperative patients with gastric cancer, and to provide person-centered oral nutrition management strategies.

METHODS

A discrete choice experiment was designed and implemented within a Chinese cancer population. The survey was administered via paper-based questionnaires during face-to-face interviews with assistance from health professionals. A mixed logit model was used to estimate respondents' preferences for different levels of nutrition therapy attributes.

RESULTS

One hundred ninety respondents valued "Adverse reactions-almost none" (β 3.43 [SE, 0.28]) the most, followed by "Flavor-good taste" (β 0.68 [SE, 0.13]) and "Follow-up frequency-once every 2 weeks" (β 0.52 [SE, 0.13]), and were willing to pay more for these attribute levels. Respondents would be 93.73% more likely to accept a nutrition therapy program if there were almost no adverse reactions compared to the frequent adverse reactions.

CONCLUSIONS

Health professionals should pay attention to the management and prevention of adverse reactions when prescribing nutritional products, and provide diversified ONS products when necessary to meet patient preferences. When formulating intervention strategies, health professionals should also consider the different characteristics of patients, acknowledge the importance of the role of nurse specialists in a novel model of multidisciplinary nutritional care, standardize ONS information, follow up regularly, and encourage patients' families to participate in daily nutrition care.

摘要

目的

胃切除术后患者对口服营养补充(ONS)治疗的依从性较差。将患者的偏好纳入治疗决策中,可以对可能的产品改进或治疗重点调整。本研究旨在调查胃癌术后患者对 ONS 治疗的偏好,并提供以患者为中心的口服营养管理策略。

方法

在中国癌症人群中设计并实施了一项离散选择实验。该调查通过纸质问卷在卫生专业人员的协助下进行面对面访谈。使用混合 logit 模型估计受访者对不同营养治疗属性水平的偏好。

结果

190 名受访者最看重“不良反应-几乎没有”(β3.43 [SE,0.28]),其次是“口味-味道好”(β0.68 [SE,0.13])和“随访频率-每 2 周一次”(β0.52 [SE,0.13]),并愿意为此类属性水平支付更多费用。与频繁出现不良反应相比,如果不良反应几乎没有,受访者接受营养治疗方案的可能性将增加 93.73%。

结论

健康专业人员在开具营养产品时应注意管理和预防不良反应,并在必要时提供多样化的 ONS 产品,以满足患者的偏好。在制定干预策略时,健康专业人员还应考虑患者的不同特征,承认护士专家在多学科营养护理新模式中的作用的重要性,规范 ONS 信息,定期随访,并鼓励患者家属参与日常营养护理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fab8/9135980/9b9ef7341869/520_2022_7154_Fig1_HTML.jpg

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