Department of Hematology, University of Schleswig-Holstein, Kiel, Germany.
Methods Mol Biol. 2022;2453:571-584. doi: 10.1007/978-1-0716-2115-8_26.
ARResT/Interrogate was built within the EuroClonality-NGS working group to meet the challenge of developing and applying assays for the high-throughput sequence-based profiling of immunoglobulin (IG) and T-cell receptor (TR) repertoires. We herein present basic concepts, outline the main workflow, delve into EuroClonality-NGS-specific aspects, and share insights from our experiences with the platform.
ARResT/Interrogate 是在 EuroClonality-NGS 工作组内构建的,旨在应对开发和应用用于高通量基于序列的免疫球蛋白 (IG) 和 T 细胞受体 (TR) 库分析的检测方法的挑战。本文介绍了基本概念,概述了主要工作流程,深入探讨了 EuroClonality-NGS 特定方面,并分享了我们使用该平台的经验。