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Oligonucleotide synthesis on a cellulose acetate functionalized with a spacer.

作者信息

Kamaike K, Yamakage S, Hasegawa Y, Ishido Y

出版信息

Nucleic Acids Symp Ser. 1986(17):89-92.

PMID:3562284
Abstract

4-(2-Hydroxyethylsulfonyl)dihydrocinnamate derivative of cellulose acetate (D.S. 1.77) was used for polymer support synthesis of oligonucleotides bearing a phosphodiester function at the 3'-terminal position, taking into consideration that the cellulose derivative is readily soluble in pyridine, but slightly soluble in a solvent such as ethanol.

摘要

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Oligonucleotide synthesis on a cellulose acetate functionalized with a spacer.
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