司库奇尤单抗治疗 Netherton 综合征。
Secukinumab use in the treatment of Netherton's syndrome.
机构信息
Department of Dermatology, Royal Children's Hospital, Melbourne, Victoria, Australia.
Faculty of Medicine, Dentistry and Health Services, The University of Melbourne, Melbourne, Victoria, Australia.
出版信息
Australas J Dermatol. 2022 Aug;63(3):365-367. doi: 10.1111/ajd.13880. Epub 2022 May 27.
PMID:35622930
Abstract
Netherton syndrome is a rare, severe genetic disorder of cornification without specific treatment. We describe two cases who demonstrated marked cutaneous improvement with secukinumab and suggest a role for IL-17 therapy in treating this condition.
摘要
Netherton 综合征是一种罕见的、严重的角化不全遗传性疾病，目前尚无特异性治疗方法。我们描述了两例使用司库奇尤单抗后皮肤明显改善的病例，并提示 IL-17 治疗在该疾病治疗中的作用。
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