Frix C D, Bronson D M
Pediatr Dermatol. 1986 Dec;3(6):464-7. doi: 10.1111/j.1525-1470.1986.tb00652.x.
A 20-month-old boy with anhidrotic ectodermal dysplasia developed fever and papulopustular skin lesions. A skin biopsy showed the histologic changes of acute miliary tuberculosis. Anhidrotic ectodermal dysplasia is characterized by an absence of seromucous glands in the oropharynx and tracheobronchial tree, making children with this disease prone to viral and bacterial respiratory infections. Mild defects in their immunologic system have also been reported. We suggest that these abnormalities may have predisposed the patient to this rare form of cutaneous tuberculosis.
一名患有无汗性外胚层发育不良的20个月大男孩出现发热和丘疹脓疱性皮肤病变。皮肤活检显示有急性粟粒性结核的组织学改变。无汗性外胚层发育不良的特征是口咽和气管支气管树中缺乏浆液黏液腺,使得患有这种疾病的儿童易患病毒和细菌性呼吸道感染。也有报道称他们的免疫系统存在轻度缺陷。我们认为这些异常情况可能使该患者易患这种罕见的皮肤结核形式。