Gaye O, Seck M, Gueye S M, Touré S A, Diallo A I, Faye B F, Thiam N M, Bousso E S, Jalloh M, Ndoye M, Niang L, Fall P A, Diop S, Gueye S M
Service d'urologie de l'Hôpital Général Idrissa Pouye, Dakar, Sénégal; Service d'urologie de l'Hôpital Dalal Jamm, Dakar, Sénégal.
Centre National Transfusion Sanguine, Dakar, Sénégal.
Prog Urol. 2022 Oct;32(12):862-867. doi: 10.1016/j.purol.2022.03.008. Epub 2022 May 24.
The objective of this study was to evaluate the sexuality of SS sickle cell patients with a history of priapism.
This was a case-control study of adult SS sickle cell patients. The occurrence of priapism as well as the nature of the priapism had been investigated. The patients were subdivided into three groups: Group 1 (no priapism), Group 2 (intermittent priapism) and Group 3 (acute priapism). The patients' sexuality was studied using the IIEF-15 questionnaire.
We interviewed 191 SS sickle cell patients. The mean age was 27.1±7.1 years. Priapism was observed in 43.5 %. Only 77 patients were eligible for the IIEF15 questionnaire. Groups 1 and 2 performed significantly better than group 3 on erectile function (EF) and orgasmic function (OF) scores. There was no significant difference in the EF and OF scores between groups 1 and 2. No significant difference was observed between the three groups for the scores of sexual desire (SD), intercourse satisfaction (IS), and overall satisfaction (OS). The impairment of erectile function in group 2 was related to the age of the first episode of priapism and the last episode. The impairment of erectile function in group 3 was related to the duration of evolution (P<0.05).
This study shows that priapism is responsible for impaired erectile function in SS adult sickle cell patients. A program to prevent intermittent episodes of priapism should be put in place.
本研究的目的是评估有阴茎异常勃起病史的镰状细胞贫血（SS）患者的性功能。
这是一项针对成年SS镰状细胞贫血患者的病例对照研究。对阴茎异常勃起的发生情况以及阴茎异常勃起的性质进行了调查。患者被分为三组：第1组（无阴茎异常勃起）、第2组（间歇性阴茎异常勃起）和第3组（急性阴茎异常勃起）。使用国际勃起功能指数-15问卷（IIEF-15）对患者的性功能进行研究。
我们采访了191名SS镰状细胞贫血患者。平均年龄为27.1±7.1岁。观察到43.5%的患者有阴茎异常勃起。只有77名患者符合IIEF-15问卷的要求。在勃起功能（EF）和性高潮功能（OF）评分方面，第1组和第2组的表现明显优于第3组。第1组和第2组在EF和OF评分上没有显著差异。三组在性欲（SD）、性交满意度（IS）和总体满意度（OS）评分上没有观察到显著差异。第2组勃起功能的损害与阴茎异常勃起首次发作和最后发作的年龄有关。第3组勃起功能的损害与病程有关（P<0.05）。
本研究表明，阴茎异常勃起是成年SS镰状细胞贫血患者勃起功能受损的原因。应制定一项预防阴茎异常勃起间歇性发作的计划。
