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基于马疗的神经康复对中风神经功能后遗症的影响:对患者功能独立性、感觉运动/认知能力及生活质量以及其照料者生活质量的影响——一项研究方案

Neurorehabilitation through Hippotherapy on Neurofunctional Sequels of Stroke: Effect on Patients' Functional Independence, Sensorimotor/Cognitive Capacities and Quality of Life, and the Quality of Life of Their Caregivers-A Study Protocol.

作者信息

Viruega Hélène, Imbernon Carole, Chausson Nicolas, Altarcha Tony, Aghasaryan Manvel, Soumah Djibril, Lescieux Edwige, Flamand-Roze Constance, Simon Olivier, Bedin Arnaud, Smadja Didier, Gaviria Manuel

机构信息

Institut Equiphoria, 48500 La Canourgue, France.

Clinical Neurosciences, Alliance Equiphoria, 48500 La Canourgue, France.

出版信息

Brain Sci. 2022 May 9;12(5):619. doi: 10.3390/brainsci12050619.

Abstract

BACKGROUND

Stroke is a high burden illness and the second leading cause of worldwide disability with generally poor recovery rates. Robust benefits of hippotherapy, a novel neurorehabilitation approach, in functional recovery following various severe neurological disabling conditions has been shown. In the present study, we will analyze the effect of a hippotherapy program on the outcome of post-stroke patients in the first year post-stroke.

METHOD

A randomized controlled clinical trial on the effectiveness of hippotherapy (4 weeks/18 weeks hippotherapy/conventional neurorehabilitation) versus conventional neurorehabilitation alone (22 weeks) will be conducted over 48 weeks. In the treated group, one-hour daily hippotherapy sessions will be exclusively conducted during the hippotherapy's cycles, alternated with periods of conventional neurorehabilitation. A test battery will measure both the functional and psychological outcomes. The primary endpoint will be the patient's functional independence. The secondary endpoints will measure the sensorimotor function, autonomy, and quality of life, as well as the caregivers' quality of life.

RESULTS AND CONCLUSION

Individual brain connectome, life history and personality construct influence the brain's functional connectivity and are central to developing optimal tailored neurorehabilitation strategies. According to our current practice, hippotherapy allows the enhancement of substantial neuroplastic changes in the injured brain with significant neurological recovery. The protocol aims to confirm those issues. Trial registration in ClinicalTrials.gov NCT04759326 accessed on 19 February 2021.

摘要

背景

中风是一种负担沉重的疾病,是全球残疾的第二大主要原因,恢复率普遍较低。已有研究表明,一种新型神经康复方法——马术疗法,在各种严重神经功能障碍后的功能恢复中具有显著益处。在本研究中,我们将分析马术疗法方案对中风后第一年患者预后的影响。

方法

将进行一项为期48周的随机对照临床试验,比较马术疗法(4周/18周马术疗法/传统神经康复)与单纯传统神经康复(22周)的有效性。在治疗组中,在马术疗法周期内每天进行1小时的马术疗法,与传统神经康复阶段交替进行。一组测试将测量功能和心理结果。主要终点将是患者的功能独立性。次要终点将测量感觉运动功能、自主性和生活质量,以及照顾者的生活质量。

结果与结论

个体脑连接组、生活史和人格结构会影响大脑的功能连接,并且对于制定最佳的个性化神经康复策略至关重要。根据我们目前的实践,马术疗法可促进受损大脑发生实质性的神经可塑性变化,并带来显著的神经功能恢复。该方案旨在证实这些问题。于2021年2月19日在ClinicalTrials.gov上注册,注册号为NCT04759326。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f05d/9139443/dfd88ef80974/brainsci-12-00619-g001.jpg

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