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智利奶牛中与指(趾)间皮炎相符的病变中 spp. 的首次分子确认

First Molecular Confirmation of spp. in Lesions Consistent with Digital Dermatitis in Chilean Dairy Cattle.

作者信息

Canales Nivia, Bustamante Hedie, Wilson-Welder Jennifer, Thomas Cristian, Ramirez Emilio, Salgado Miguel

机构信息

Laboratorio de Enfermedades Infecciosas, Instituto de Medicina Preventiva Veterinaria, Facultad de Ciencias Veterinarias, Universidad Austral de Chile, Casilla, P.O. Box 567, Valdivia 5090000, Chile.

Escuela de Graduados, P.O. Box 567, Valdivia 5090000, Chile.

出版信息

Pathogens. 2022 Apr 26;11(5):510. doi: 10.3390/pathogens11050510.

DOI:10.3390/pathogens11050510
PMID:35631031
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9145681/
Abstract

Digital dermatitis (DD) is a highly contagious and infectious disease in cattle which has a considerable negative economic impact worldwide, and adversely affects animal welfare. Members of the genus are the only bacterial agents for which there is consistent evidence of participation in DD lesions. In Chile, DD has been described since the 1990s, but only under a clinical approach. To date, the presence of the pathogenic agent has not been confirmed in Chile by any type of confirmatory microbiological diagnosis. The aim of the present study was to detect the presence of spp. DNA in lesions consistent with DD, in Chilean dairy cattle for the first time. We provide PCR confirmation of spp. in Chilean dairy cattle affected by DD. The high rate of positive results, as well as the proportion of the main species involved, is in line with what have been described in published studies elsewhere. Future herd control plans should benefit from the molecular detection of these pathogenic bacteria associated with DD.

摘要

趾间皮炎(DD)是牛的一种高度传染性疾病,在全球范围内造成了相当大的负面经济影响,并对动物福利产生不利影响。该属成员是唯一有确凿证据参与DD病变的细菌病原体。在智利,自20世纪90年代以来就已描述了趾间皮炎,但仅采用临床方法。迄今为止,智利尚未通过任何类型的确诊微生物诊断证实病原体的存在。本研究的目的是首次在智利奶牛中检测与趾间皮炎相符的病变中是否存在该属细菌的DNA。我们通过PCR证实了智利患趾间皮炎的奶牛中存在该属细菌。高阳性率以及主要相关菌种的比例与其他地方发表的研究中所描述的一致。未来的牛群控制计划应受益于对这些与趾间皮炎相关的致病细菌的分子检测。

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本文引用的文献

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Detection of treponemes in digital dermatitis lesions of captive European bison (Bison bonasus).检测圈养欧洲野牛(Bison bonasus)的数字性皮炎病变中的密螺旋体。
PLoS One. 2021 Aug 9;16(8):e0255921. doi: 10.1371/journal.pone.0255921. eCollection 2021.
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Treponema spp., the dominant pathogen in the lesion of bovine digital dermatitis and its characterization in dairy cattle.密螺旋体属,在奶牛digital dermatitis 病变中的主要病原体及其在奶牛中的特征。
Vet Microbiol. 2020 Jun;245:108696. doi: 10.1016/j.vetmic.2020.108696. Epub 2020 Apr 25.
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Consumers' Concerns and Perceptions of Farm Animal Welfare.
消费者对农场动物福利的关注与认知。
Animals (Basel). 2020 Feb 27;10(3):385. doi: 10.3390/ani10030385.
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Detection of specific Treponema species and Dichelobacter nodosus from digital dermatitis (Mortellaro's disease) lesions in Swiss cattle.瑞士奶牛蹄叶炎(莫泰拉罗病)病变中特定密螺旋体属物种和坏死梭杆菌的检测
Schweiz Arch Tierheilkd. 2019 Apr;161(4):207-215. doi: 10.17236/sat00201.
5
Associations between digital dermatitis lesion grades in dairy cattle and the quantities of four Treponema species.奶牛数字皮炎病变等级与四种密螺旋体数量的关系。
Vet Res. 2018 Oct 29;49(1):111. doi: 10.1186/s13567-018-0605-z.
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Treponeme-Associated Hoof Disease of Free-Ranging Elk ( Cervus elaphus) in Southwestern Washington State, USA.美国华盛顿州西南部自由放养麋鹿(马鹿)的密螺旋体相关蹄病
Vet Pathol. 2019 Jan;56(1):118-132. doi: 10.1177/0300985818798108. Epub 2018 Sep 24.
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Pathology and bacteria related to digital dermatitis in dairy cattle in all year round grazing system in Brazil.巴西全年放牧系统中奶牛的数字性皮炎相关病理学和细菌。
PLoS One. 2018 Mar 7;13(3):e0193870. doi: 10.1371/journal.pone.0193870. eCollection 2018.
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A novel approach to probe host-pathogen interactions of bovine digital dermatitis, a model of a complex polymicrobial infection.一种探究牛趾间皮炎宿主-病原体相互作用的新方法,牛趾间皮炎是一种复杂的多微生物感染模型。
BMC Genomics. 2016 Dec 1;17(1):987. doi: 10.1186/s12864-016-3341-7.
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Vet Dermatol. 2016 Apr;27(2):106-12e29. doi: 10.1111/vde.12286. Epub 2016 Jan 21.