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白蛉肠道提取物对红细胞和利什曼原虫的凝集作用:凝集素活性的证据。

The agglutination of erythrocytes and Leishmania parasites by sandfly gut extracts: evidence for lectin activity.

作者信息

Wallbanks K R, Ingram G A, Molyneux D H

出版信息

Trop Med Parasitol. 1986 Dec;37(4):409-13.

PMID:3563322
Abstract

Lysates of heads, hind- and midguts of male and female Phlebotomus papatasi were found to contain lectins or lectin-like molecules capable of agglutinating human red blood cell types of the ABO(H) system and promastigotes of Leishmania aethiopica, L. major and L. donovani but not L. hertigi hertigi promastigotes or Crithidia fasciculata choanomastigotes. The agglutination of erythrocytes from the human O Rhesus positive blood group by sandfly midgut extracts was inhibited by two disaccharides; trehalose and turanose. This is the first report of haemagglutinating and parasite agglutinating activity in sandflies (Psychodidae).

摘要

已发现雄性和雌性巴氏白蛉头部、后肠和中肠的裂解物含有能够凝集ABO(H)系统人类红细胞类型以及埃塞俄比亚利什曼原虫、硕大利什曼原虫和杜氏利什曼原虫前鞭毛体的凝集素或类凝集素分子,但不能凝集赫氏利什曼原虫前鞭毛体或粗短克氏鞭毛虫漏斗形鞭毛体。白蛉中肠提取物对人类O型恒河猴阳性血型红细胞的凝集作用被两种二糖(海藻糖和松二糖)抑制。这是关于白蛉(毛蠓科)中血凝和寄生虫凝集活性的首次报道。

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The agglutination of erythrocytes and Leishmania parasites by sandfly gut extracts: evidence for lectin activity.白蛉肠道提取物对红细胞和利什曼原虫的凝集作用:凝集素活性的证据。
Trop Med Parasitol. 1986 Dec;37(4):409-13.
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