Department of Urology, Bir Hospital, National Academy of Medical Sciences, Kathmandu, Nepal.
Sorbonne University GRC Urolithiasis No. 20 Tenon Hospital, 75020, Paris, France.
World J Urol. 2022 Jul;40(7):1839-1844. doi: 10.1007/s00345-022-04040-0. Epub 2022 May 28.
To compare the efficacy of conventional low power and high power holmium: yttrium aluminum-garnet (Ho: YAG) laser lithotripsy settings during retrograde intrarenal surgery (RIRS). METHODS: The prospective study was conducted in patients undergoing RIRS for renal stones less than 2 cm diameter. Pulsed Ho:YAG laser (Lumenis Pulse TM P120 H) was used for laser lithotripsy and the patients were randomized into low power (LP) and high power (HP) laser lithotripsy settings groups. The lasing duration, total laser energy used (Joules), laser energy used to ablate 1 mm of stone (Joules/mm), operative duration, stone ablation speed (mm/s) and stone free rate were compared.
A total of 120 underwent RIRS with 63 and 57 patients in LP and HP group, respectively. Median stone volume and stone density were comparable between the groups. The total energy used and laser energy used to ablate 1mm of stone (Joules/mm) were significantly higher in the HP group than in LP group (27.9 (16.4-46.2) J/ mm vs 9.7 (5.3-17.7) J/ mm) (p < 0.01). Median (IQR) ablation speed were 0.8 (0.5-1.3) mm/s and 0.6 (0.4-1) mm/s in the LP and HP groups, respectively. The median lasing time, operative time and stone free rate were similar in both the groups.
The total energy used and J/mm were lower in the LP group than in HP group with similar lasing duration, operative duration, ablation speed and stone free rate for renal stones less than 2 cm.
比较逆行性肾内手术(RIRS)中常规低功率和高功率钬:钇铝石榴石(Ho:YAG)激光碎石术设置的疗效。
本前瞻性研究纳入了接受直径小于 2cm 肾结石 RIRS 的患者。采用脉冲 Ho:YAG 激光(Lumenis Pulse TM P120 H)进行激光碎石,患者随机分为低功率(LP)和高功率(HP)激光碎石术组。比较激光持续时间、总激光能量(焦耳)、用于消融 1mm 结石的激光能量(焦耳/mm)、手术时间、结石消融速度(mm/s)和结石清除率。
共 120 例患者接受 RIRS,LP 组和 HP 组分别有 63 例和 57 例。两组的结石体积中位数和结石密度中位数无差异。HP 组的总能量使用量和用于消融 1mm 结石的激光能量(焦耳/mm)明显高于 LP 组(27.9(16.4-46.2)J/ mm vs 9.7(5.3-17.7)J/ mm)(p<0.01)。LP 组和 HP 组的中位(IQR)消融速度分别为 0.8(0.5-1.3)mm/s 和 0.6(0.4-1)mm/s。两组的激光持续时间、手术时间和结石清除率中位数相似。
对于直径小于 2cm 的肾结石,LP 组的总能量使用量和 J/mm 低于 HP 组,激光持续时间、手术时间、消融速度和结石清除率相似。