Department of Rehabilitation, Kamiiida Daiichi General Hospital, 2-70 Kamiiida-kitamachi, Kita-ku, Nagoya, Aichi 462- 0802, Japan.
Program in Physical and Occupational Therapy, Nagoya University Graduate School of Medicine, 1-1-20 Daikominami, Higashi-ku, Nagoya, Aichi 461-8673, Japan.
Asian Pac J Cancer Prev. 2022 May 1;23(5):1753-1759. doi: 10.31557/APJCP.2022.23.5.1753.
Postoperative delirium (POD) is one of the most common postoperative complications in gastrointestinal surgery patients. POD has been reported to affect long-term activities of daily living, cognitive function decline, and mortality. Previous studies have indicated that preoperative physical activity (PA) predicted POD in patients with other diseases, but we have not found any reports in patients with gastrointestinal cancer. In this retrospective study, we investigated the relationship between preoperative PA and POD in gastrointestinal cancer patients.
POD was diagnosed based on the short confusion assessment method. We divided patients into active and inactive groups based on their preoperative PA assessed by the International Physical Activity Questionnaire (Japanese version). Multivariate logistic analysis was conducted to investigate the association between preoperative PA and POD.
POD occurred in 25 of the 151 patients (16.6%). Preoperative low PA was associated with POD after adjusting for confounders, namely, diabetes mellitus, sedentary time, and usual gait speed (odds ratio, 2.83; 95% confidence interval: 1.06-7.58; p=0.03).
Preoperative low PA was a predictor of POD independent of the confounding factors in patients with gastrointestinal cancer.
术后谵妄（POD）是胃肠外科患者最常见的术后并发症之一。有报道称，POD 会影响患者的日常活动能力、认知功能下降和死亡率。既往研究表明，术前体力活动（PA）可预测其他疾病患者的 POD，但我们尚未在胃肠癌患者中发现相关报道。在这项回顾性研究中，我们调查了胃肠癌患者术前 PA 与 POD 之间的关系。
采用简短认知评估方法诊断 POD。根据国际体力活动问卷（日本版）评估的术前 PA，我们将患者分为活跃组和不活跃组。采用多变量 logistic 分析探讨术前 PA 与 POD 之间的关系。
在 151 例患者中，25 例（16.6%）发生 POD。在校正混杂因素，即糖尿病、久坐时间和通常的步速后，术前低 PA 与 POD 相关（比值比，2.83；95%置信区间：1.06-7.58；p=0.03）。
术前低 PA 是胃肠癌患者 POD 的独立预测因素，不受混杂因素的影响。
