Erasmus University Rotterdam, P.O. Box 1738, 3000 DR Rotterdam, The Netherlands.
Endeavour. 2022 Mar-Jun;46(1-2):100816. doi: 10.1016/j.endeavour.2022.100816. Epub 2022 May 27.
Whereas the Human Genome Project was an anthropocentric research endeavour, microbiome research entails a much more interactive and symbiotic view of human existence, seeing human beings as holobionts, a term coined by Lynn Margulis to emphasise the interconnectedness and multiplicity of organisms. In this paper, building on previous authors, a dialectical perspective on microbiome research will be adopted, striving to supersede the ontological divide between self and other, humans and microbes, and to incorporate the microbiome as a crucial dimension of human existence, not only corporally, but also in terms of mood and cognition. On the practical level, microbiome insights promise to offer opportunities for self-care and self-management, allowing us to consciously interact with our microbiome to foster wellness and health. How to distinguish realistic scenarios from hype? Here again, an interactive (dialectical) approach is adopted, arguing that practices of the self should result from mutual learning between laboratory research and life-world experience.
虽然人类基因组计划是一项以人类为中心的研究工作，但微生物组研究需要对人类的存在有一个更加互动和共生的观点，将人类视为整体生物，这是 Lynn Margulis 创造的一个术语，强调生物体的相互联系和多样性。在本文中，在前人研究的基础上，采用了一种辩证的微生物组研究视角，努力超越自我与他者、人类与微生物之间的本体论鸿沟，并将微生物组作为人类存在的一个重要维度，不仅在身体上，而且在情绪和认知上。在实践层面上，微生物组的研究成果有望为自我护理和自我管理提供机会，使我们能够有意识地与微生物组互动，促进健康和健康。如何将现实场景与炒作区分开来？在这里，同样采用了一种互动（辩证）的方法，认为自我实践应该来自实验室研究和生活世界经验之间的相互学习。
