Total laryngectomy negatively impacts sinonasal and olfactory-specific quality of life.
作者信息
Chen Joy, Solis Roberto N, Mehrzad Mehrnaz, Gill Amarbir, Garber Beverly, Beliveau Angela M, Bewley Arnaud F, Steele Toby O, Birkeland Andrew C, Abouyared Marianne
机构信息
University of California, Davis, Department of Otolaryngology, Sacramento, CA, United States of America.
University of Utah, Department of Otolaryngology, Salt Lake City, UT, United States of America.
出版信息
Am J Otolaryngol. 2022 Jul-Aug;43(4):103471. doi: 10.1016/j.amjoto.2022.103471. Epub 2022 May 5.
PURPOSE
The purpose of this study is to characterize deficits in olfactory-specific and sinonasal-specific QoL after total laryngectomy (TL) with validated patient reported outcome measures.
METHODS
Thirty patients who had a TL were prospectively enrolled. Patient demographics, as well as scores from the Questionnaire of Olfactory Disorders Negative Statements (QOD-NS) and the Sino-nasal Outcome Test-22 (SNOT-22) were collected. Univariate analysis was performed to assess associations between patient characteristics and QoL scores.
RESULTS
The average QOD-NS score was 37.9 ± 11.4 (<38.5 is considered abnormal) and average SNOT-22 score was 32.0 ± 3.8 (>20 indicates a moderate/severe impact on QoL). The abnormal QOD-NS group had a greater percentage of former smokers compared to the normal group (77.8% vs. 58.1%; P = 0.56) and more median days from surgery compared to the normal group (904 vs. 477 days; P = 0.24).
CONCLUSIONS
Olfactory dysfunction associated with TL results in blunting of olfactory-specific QoL.
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