Department of Pathological Anatomy, FMPM-UCA-CHU Mohamed VI, 40000, Marrakech, Morocco.
Department of Otolaryngology, FMPM-UCA-CHU Mohamed VI, 40000, Marrakech, Morocco.
Diagn Pathol. 2022 May 30;17(1):48. doi: 10.1186/s13000-022-01226-3.
Malignant schwannoma is a malignant tumor of differentiation of Schwann cells or perineural cells.
The patient was a 74-year-old woman with no particular pathological history. She presented swallowing difficulty of solids and odynophagia, evolving for 1 year. Physical examination revealed a budding tumor of the left palatine tonsil without cervical adenopathy. The CT scan confirmed the lesions and the absence of tumor extensions. Histological and immunohistochemical examination of the biopsy sample of the tonsil tumor concluded to be a malignant schwannoma. The patient underwent a tonsillectomy with postoperative follow-up.
Malignant schwannomas are aggressive tumors. They usually occur in young adults. They mainly affect nerves and soft tissues. Occurrence in the amygdala is rare.
The association of malignant schwannoma of the palatine tonsil and advanced age is rare.
恶性神经鞘瘤是一种分化为雪旺细胞或神经周围细胞的恶性肿瘤。
患者为 74 岁女性，无特殊病史。1 年来她出现固体吞咽困难和吞咽疼痛。体格检查发现左腭扁桃体有芽状肿瘤，无颈部淋巴结病。CT 扫描证实了病变的存在，并且没有肿瘤扩散。扁桃体肿瘤活检样本的组织学和免疫组织化学检查结果为恶性神经鞘瘤。患者接受了扁桃体切除术，并进行了术后随访。
恶性神经鞘瘤是一种侵袭性肿瘤。它们通常发生在年轻人中。它们主要影响神经和软组织。发生在杏仁核的情况较为罕见。
腭扁桃体恶性神经鞘瘤与高龄相关的情况较为罕见。
