Garnick Kelly, Wetherby Anthony E, Sweeney Brian, Scott Thomas A, Wei Cong
Food and Drug Administration/Winchester Engineering and Analytical Center, 109 Holton St, Winchester, MA 01890, USA.
J Radioanal Nucl Chem. 2021 Oct 29;330:979-984. doi: 10.1007/s10967-021-08019-w.
A rapid analytical method for quantifying Sr in infant formula prior to secular equilibrium is presented. The approach is dependent on the use of two separations of Sr from Y, with the first providing an Y ingrowth start point and the second providing an Y ingrowth end point. Data were obtained at activity concentrations of approximately 6 Bq/kg and 160 Bq/kg, the latter of which is representative of the US Food and Drug Administration (FDA) Derived Intervention Levels (DIL). Experiments were designed to collect data from ingrowth periods ranging from 16 h to 2 weeks. Activities obtained with a separation interval as low as 16 h ranged from 92.7 to 109.4% of the known value. When Y ingrowth was allowed to occur for 24 h or longer, the activities ranged from 93.2 to 106.2% of the known value and the precision of this group improved from 5.2 to 3.1%. The limit of quantification (LOQ) was 0.5 Bq/kg using 250 g sample portions.
本文介绍了一种在达到长期平衡之前对婴儿配方奶粉中锶进行定量分析的快速方法。该方法依赖于将锶与钇进行两次分离，第一次分离提供钇生长起始点，第二次分离提供钇生长终点。在大约6 Bq/kg和160 Bq/kg的活度浓度下获取数据，后者代表美国食品药品监督管理局（FDA）的推导干预水平（DIL）。实验设计用于收集生长时间从16小时到2周的数据。分离间隔低至16小时时获得的活度为已知值的92.7%至109.4%。当钇生长24小时或更长时间时，活度为已知值的93.2%至106.2%，且该组的精密度从5.2%提高到3.1%。使用250克样品时，定量限（LOQ）为0.5 Bq/kg。
