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剖宫产术中脊髓麻醉失败的类型、管理及相关因素。前瞻性队列研究。

Type, management, and associated factors of failed spinal anesthesia in cesarean section. Prospective cohort study.

作者信息

Bekele Zenebe, Jisha Hunduma

机构信息

Ambo University, Ambo, Ethiopia.

出版信息

Ann Med Surg (Lond). 2022 Apr 22;77:103616. doi: 10.1016/j.amsu.2022.103616. eCollection 2022 May.

Abstract

BACKGROUND

Spinal anesthesia is an anesthesia technique suitable for cesarean section to avoid respiratory complications. However, the management of spinal anesthesia is very important because spinal anesthesia may fail and the patient may be exposed to pain and discomfort.

OBJECTIVE

To assess the type, management, and related factors of failure of spinal anesthesia at cesarean section.

METHODS

Multicenter prospective cohort study was conducted at a public hospital in Addis Ababa on 794 mothers who met the criteria for cesarean section under spinal anesthesia. Data collection methods were adopted, including chart reviews and observations of spinal anesthesia procedures. The data collected was entered in Epi info version 7 and analyzed in SPSS version 20. Independent variables with dependent variables were analyzed using logistic regression. A p-value of 0.05 for & it; was considered a statistically significant test cutoff.

RESULT

Of 121 failed spinal anesthesia 35 were complete and 86 were partial failed spinal anesthesia from those complete failed spinal anesthesia were managed by repeating spinal and converting to general anesthesia and partial failed spinal anesthesia were managed by the supplementary drug. Experience of the anesthetist <1 (AOR = 4.12, 95% CI, 2.47-6.90), patient position (AOR = 14.43,95%CL, 2.65-78.61), number of attempts>1 (AOR = 9.26, 95% CI, 5.69-15.01), bloody CSF (AOR = 6.37, 95%CI, 2.90-13.96), BMI ≥30kgm2 (AOR = 2.03, 95%CI, 1.12-3.68) and dose of bupivacaine <10 mg (AOR = 2.72, 95% CI, 1.33-5.53) were found to be statistically significant associated with failed spinal anesthesia.

CONCLUSION AND RECOMMENDATION

Experience of anesthetists (<1 year), obesity, bupivacaine dose <10 mg, bloody appearance of CSF, number of attempts> 1 were associated factors for failed spinal anesthesia in cesarean section. Our failed spinal management is not the same among hospitals and does not follow recommended failed spinal management. Up-skilling of anesthesia professionals should be considered on identified associated factors of failed spinal anesthesia and management of failed spinal anesthesia should be based on the recommended guidelines.

摘要

背景

脊髓麻醉是一种适用于剖宫产以避免呼吸并发症的麻醉技术。然而,脊髓麻醉的管理非常重要,因为脊髓麻醉可能失败,患者可能会遭受疼痛和不适。

目的

评估剖宫产脊髓麻醉失败的类型、管理及相关因素。

方法

在亚的斯亚贝巴的一家公立医院对794名符合脊髓麻醉下剖宫产标准的母亲进行了多中心前瞻性队列研究。采用了数据收集方法,包括病历回顾和脊髓麻醉程序观察。收集的数据录入Epi info 7版本,并在SPSS 20版本中进行分析。使用逻辑回归分析自变量和因变量。p值<0.05被认为是具有统计学意义的检验临界值。

结果

在121例脊髓麻醉失败病例中,35例为完全失败,86例为部分失败。对于完全失败的脊髓麻醉,通过重复脊髓麻醉和转为全身麻醉进行处理;对于部分失败的脊髓麻醉,通过补充药物进行处理。麻醉医生经验<1年(比值比=4.12,95%可信区间,2.47-6.90)、患者体位(比值比=14.43,95%可信区间,2.65-78.61)、穿刺次数>1次(比值比=9.26,95%可信区间,5.69-15.01)、脑脊液带血(比值比=6.37,95%可信区间,2.90-13.96)、体重指数≥30kg/m²(比值比=2.03,95%可信区间,1.12-3.68)以及布比卡因剂量<10mg(比值比=2.72,95%可信区间,1.33-5.53)被发现与脊髓麻醉失败具有统计学显著相关性。

结论与建议

麻醉医生经验<1年、肥胖、布比卡因剂量<10mg、脑脊液带血外观、穿刺次数>1次是剖宫产脊髓麻醉失败的相关因素。我们医院之间脊髓麻醉失败的处理方式不同,且未遵循推荐的脊髓麻醉失败处理方法。应考虑针对已确定的脊髓麻醉失败相关因素对麻醉专业人员进行技能提升,并且脊髓麻醉失败的处理应基于推荐指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/954d/9142661/44272452615e/gr1.jpg

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