Maxwell R J, Greenfield L J
Surgery. 1987 Apr;101(4):389-94.
The late mortality in 167 patients who had Greenfield vena caval filters inserted after episodes of acute pulmonary embolism is reported. The mean follow-up period of the survivors was 42 months; the mean survival time of the 48% who died was 9.3 months. The mortality rate in 50 comparable patients who did not have pulmonary embolism but had prophylactic filter insertion was 52% with a mean survival time of 9.4 months. The mean follow-up period of the survivors was 28 months. Age, mean pulmonary artery pressure, and severity of the initial embolic episode did not predict the increased rate of late mortality. We conclude that for patients who survive acute pulmonary embolism and have treatment to prevent recurrence, the embolic history of thromboembolism has little impact on late mortality, which is determined by their preexisting serious medical conditions.
报告了167例在急性肺栓塞发作后植入格林菲尔德腔静脉滤器患者的晚期死亡率。幸存者的平均随访期为42个月;死亡的48%患者的平均生存时间为9.3个月。50例未发生肺栓塞但接受预防性滤器植入的对照患者的死亡率为52%,平均生存时间为9.4个月。幸存者的平均随访期为28个月。年龄、平均肺动脉压和初始栓塞发作的严重程度并不能预测晚期死亡率的增加。我们得出结论,对于急性肺栓塞存活且接受预防复发治疗的患者,血栓栓塞的栓塞病史对晚期死亡率影响很小,晚期死亡率由其先前存在的严重疾病决定。