沙特阿拉伯的个体克罗恩病患者的健康相关生活质量：样本研究。

Health-Related Quality of Life in Individuals with Crohn's Disease: A Sample from Saudi Arabia.

机构信息

Clinical Nutrition Program, Dep. of Health, College of Health and Rehabilitation Sciences, Princess Nourah bint Abdulrahman University, PO Box 84428, Riyadh, Saudi Arabia. Tel +966591215580.

出版信息

J Allied Health. 2022 Summer;51(2):104-109.

PMID:35640288

Abstract

BACKGROUND

This study was conducted to compare health-related quality of life between adults with Crohn's disease (CD) and healthy controls (CONs).

METHODS

A comparative cross-sectional study was conducted on adults with CD and CONs in Saudi Arabia (aged 18-60 years). Sociodemographic data (area of residence, education level, employment, and marital status) were collected from both groups, as well as additional information including disease onset, treatment, and symptomology from the CD group. The validated Arabic version of the quality of life tool was used to assess health-related quality of life.

RESULTS

A total of 109 CD patients and 370 CONs participated in this study. The patients with CD had significantly lower health-related quality of life scores for physical functioning [CD 75 (50-90), CON 85 (60-95)], role physical [CD 50 (0-100), CON 100 (50-100)], role emotional [CD 67 (0-100), CON 67 (33-100)], vitality [CD 50 (30-58), CON 50 (40-60)], social functioning [CD 63 (50-75), CON 75 (50-88)], bodily pain [CD 70 (45-90), CON 80 (68-100)], and general health [CD 55 (40-65), CON 65 (55-75)]. The physical and mental domain scores were lower in the CD group [63 (52-75) and 51 (32-69)] than CONs group [75 (63-85) and 63 (55-72)], respectively (p<0.02).

CONCLUSION

The CD group had a lower health-related quality of life than the CONs.

摘要

背景

本研究旨在比较成人克罗恩病（CD）患者与健康对照者（CONs）的健康相关生活质量。

方法

在沙特阿拉伯进行了一项成人 CD 患者和 CONs 的比较性横断面研究（年龄 18-60 岁）。从两组人群中收集社会人口统计学数据（居住区域、教育水平、就业和婚姻状况），并从 CD 组中收集更多信息，包括疾病发作、治疗和症状。使用经过验证的阿拉伯语版本生活质量工具评估健康相关生活质量。

结果

共有 109 例 CD 患者和 370 例 CONs 参与了这项研究。CD 患者的生理功能[CD 75（50-90），CON 85（60-95）]、生理角色[CD 50（0-100），CON 100（50-100）]、情绪角色[CD 67（0-100），CON 67（33-100）]、活力[CD 50（30-58），CON 50（40-60）]、社会功能[CD 63（50-75），CON 75（50-88）]、躯体疼痛[CD 70（45-90），CON 80（68-100）]和一般健康[CD 55（40-65），CON 65（55-75）]等健康相关生活质量评分明显较低。CD 组的生理和心理领域评分也低于 CONs 组[63（52-75）和 51（32-69）]，分别为[75（63-85）和 63（55-72）]（p<0.02）。