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胸腺瘤切除术治疗抗 N- 甲基-D-天冬氨酸受体脑炎。

Thymectomy for treatment of anti-NMDA receptor encephalitis.

机构信息

University of Massachusetts T.H. Chan School of Medicine, Worcester, MA, USA.

出版信息

Eur J Cardiothorac Surg. 2022 Sep 2;62(4). doi: 10.1093/ejcts/ezac329.

Abstract

In this case report, we present a 25-year-old woman who was diagnosed with anti-N-methyl-D-aspartate (NMDA) receptor encephalitis and subsequently was found to have thymic hyperplasia. She underwent robotic bilateral access thymectomy for treatment of her anti-NMDA receptor encephalitis and has remained asymptomatic after her operation without any medication. This is only the second reported case of thymectomy for treatment of this condition. This case may further suggest thymic tissue is involved in the development of anti-NMDA receptor encephalitis and that thymectomy is an appropriate treatment for a subset of patients with this disease.

摘要

在本病例报告中,我们介绍了一位 25 岁的女性,她被诊断患有抗 N-甲基-D-天冬氨酸(NMDA)受体脑炎,随后发现患有胸腺瘤。她接受了机器人双侧入路胸腺切除术治疗抗 NMDA 受体脑炎,术后无任何药物治疗,一直无症状。这是该病症治疗中报告的第二例胸腺切除术。该病例可能进一步表明胸腺组织参与了抗 NMDA 受体脑炎的发生,并且胸腺切除术是该疾病患者亚组的一种合适治疗方法。

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