Department of Ophthalmology and Vision Science, Eye & ENT Hospital, Shanghai Medical School, Fudan University, Shanghai, People's Republic of China.
NHC Key Laboratory of Myopia, Fudan University, Shanghai, People's Republic of China.
Br J Ophthalmol. 2023 Sep;107(9):1377-1382. doi: 10.1136/bjophthalmol-2021-320751. Epub 2022 May 31.
To report the effect of two three-muscle surgeries, inferior rectus belly transposition plus augmented superior rectus transposition plus medial rectus recession (ISM) and modified vertical rectus belly transposition plus medial rectus recession (VM), in the management of large-angle esotropia in Chinese patients with chronic sixth nerve palsy.
Twenty-eight consecutive patients with large-angle esotropia ≥50 were prospectively enrolled and underwent either ISM or VM. Main outcomes included preoperative and postoperative deviation in primary position, abduction limitation and complications. Follow-up was at least 6 months.
Of the included patients, 13 underwent ISM and 15 underwent VM. Preoperatively, ISM group displayed larger esotropia and more severe abduction limitation. 27 patients completed the follow-up. The postoperative horizontal deviation and abduction limitation were similar in both groups. At the last follow-up, ISM group demonstrated greater improvement of abduction limitation than VM group in both grading (group difference -2.1, p<0.001) and quantitation (group difference 2.6 mm, p=0.001). However, eight (30%) patients revealed an induced adduction limitation ≤-1. Of the 22 patients with unilateral palsy, more esotropia of 14.8 was corrected in ISM group, compared with VM group (p=0.003). Three patients (14%) developed vertical diplopia and three (14%) developed torsional diplopia. Unexpectedly, keratitis was observed in 4 of 27 (15%) patients, all with concurrent fifth and/or seventh nerve palsy. Three patients aggravated to corneal ulceration.
Two three-muscle surgeries, ISM and VM were both effective for large-angle esotropia in Chinese patients with chronic sixth nerve palsy. However, attention should be paid to potential complications.
报告两种三肌肉手术,下直肌腹移位加增强上直肌转位加内直肌后退(ISM)和改良垂直直肌腹转位加内直肌后退(VM),在治疗中国慢性第六神经麻痹的大角度内斜视患者中的效果。
连续 28 例大角度内斜视≥50 的患者前瞻性纳入并接受 ISM 或 VM 治疗。主要结果包括在第一眼位的术前和术后偏斜、外展受限和并发症。随访至少 6 个月。
包括的患者中,13 例接受 ISM,15 例接受 VM。ISM 组术前斜视度更大,外展受限更严重。27 例患者完成了随访。两组术后水平偏斜和外展受限相似。在最后一次随访时,ISM 组在分级(组间差异-2.1,p<0.001)和定量(组间差异 2.6mm,p=0.001)方面均显示出更大的外展受限改善。然而,8 名(30%)患者出现了≤-1 的继发性内收受限。在 22 例单侧麻痹患者中,ISM 组的 14.8 度内斜视得到了更多的矫正,与 VM 组相比(p=0.003)。3 名患者(14%)出现垂直复视,3 名患者(14%)出现扭转复视。出乎意料的是,27 例患者中有 4 例(15%)出现了角膜炎,均伴有第五和/或第七神经麻痹。3 名患者加重为角膜溃疡。
两种三肌肉手术,ISM 和 VM 对于中国慢性第六神经麻痹的大角度内斜视均有效。然而,应注意潜在的并发症。