Division of Pediatrics and Patient Care, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Department of Pediatrics, Duke University School of Medicine, Durham, NC, USA.
Oncologist. 2022 Mar 4;27(2):135-143. doi: 10.1093/oncolo/oyab049.
Compared with their ensured counterparts, uninsured adolescents and young adults (AYAs) with cancer are more likely to present with advanced disease and have poor prognoses. The Patient Protection and Affordable Care Act (ACA), enacted in 2010, provided health care coverage to millions of uninsured young adults by allowing them to remain on their parents' insurance until age 26 years (the Dependent Care Expansion, DCE). The impact of the expansion of insurance coverage on survival outcomes for young adults with cancer has not been assessed.
Utilizing the Surveillance, Epidemiology, and End Results database, we identified all patients aged 12-16 (younger-AYAs), 19-23 (middle-AYAs), and 26-30 (older-AYAs) who were diagnosed with cancer between 2006-2008 (pre-ACA) and 2011-2013 (post-ACA).
In this population-based cohort study, we used an accelerated failure time model to assess changes in survival rates before and after the enactment of the ACA DCE.
Middle-AYAs ages 19-23 (thus eligible to remain on their parents' insurance) experienced significantly increased 2-year survival after the enactment of the ACA DCE (survival time ratio 1.25, 95% confidence interval: 0.75-2.43, P = .029) and that did not occur in younger-AYAs (ages 12-16). Patients with sarcoma and acute myeloid leukemia accounted for the majority of improvement in survival. Middle-AYAs of hispanic ethnicity and those with low socioeconomic status experienced trends of improved survival after the ACA DCE was enacted.
Survival outcomes improved for young adults with cancer following the expansion of health insurance coverage. Efforts are needed to expand coverage for the millions of young adults who do not have health insurance.
与有保险的同龄人相比,患有癌症的未参保青少年和年轻人(AYAs)更有可能出现晚期疾病且预后较差。2010 年颁布的《患者保护与平价医疗法案》(ACA)允许年轻人在 26 岁之前继续使用父母的保险,为数百万没有保险的年轻人提供了医疗保险。该法案扩大了保险范围,但其对癌症青年患者生存结果的影响尚未得到评估。
我们利用监测、流行病学和最终结果数据库,确定了所有在 2006 年至 2008 年(ACA 之前)和 2011 年至 2013 年(ACA 之后)期间被诊断患有癌症的年龄在 12-16 岁(年轻 AYAs)、19-23 岁(中 AYAs)和 26-30 岁(年长 AYAs)的患者。
在这项基于人群的队列研究中,我们使用加速失效时间模型来评估 ACA DCE 颁布前后生存率的变化。
19-23 岁的中 AYAs(因此有资格继续使用父母的保险)在 ACA DCE 颁布后,2 年生存率显著提高(生存时间比 1.25,95%置信区间:0.75-2.43,P =.029),而年轻 AYAs(12-16 岁)则没有。肉瘤和急性髓系白血病患者的生存率提高幅度最大。具有西班牙裔血统和社会经济地位较低的中 AYAs 在 ACA DCE 颁布后,生存率呈上升趋势。
医疗保险范围扩大后,癌症青年患者的生存结果得到改善。需要努力扩大数百万没有医疗保险的年轻人的覆盖范围。