Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan.
Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kanazawa University, Kanazawa, Japan;
Anticancer Res. 2022 Jun;42(6):3143-3150. doi: 10.21873/anticanres.15803.
BACKGROUND/AIM: The thigh is divided into the anterior, medial, and posterior compartments, and malignant soft tissue tumours can occur in any compartment of the thigh. This study analysed the relationship between various factors, particularly tumour location and clinical outcome, in patients with primary soft tissue sarcoma of the thigh.
Seventy-four patients were included in this retrospective study. The relationships between variables and prognosis were statistically analysed.
Multivariate analysis of the patient clinical data demonstrated that seromas developed more often in the medial compartment tumours and postoperative complications excluding seroma occurred more frequently in patients with two or more muscles resected or stage III tumours. A low Musculoskeletal Tumor Society score was associated with a long operative time (more than 120 min), anterior compartment tumours, and more than two muscle resections. In addition, soft tissue sarcomas in the medial compartment and stage III sarcomas were associated with a low 5-year metastasis-free survival.
Soft tissue sarcomas in the medial compartment were associated with postoperative seroma and metastasis, whereas sarcomas in the anterior compartment correlated with low postoperative function.
背景/目的：大腿可分为前、内、后三个间隔，恶性软组织肿瘤可发生于大腿的任何间隔。本研究分析了原发性大腿软组织肉瘤患者中各种因素（尤其是肿瘤位置和临床结果）之间的关系。
本回顾性研究纳入了 74 名患者。对变量与预后之间的关系进行了统计学分析。
对患者临床资料的多变量分析表明，黏液肿更常发生于内侧间隔肿瘤，术后并发症（不包括黏液肿）更常发生于切除两个或更多肌肉或 III 期肿瘤的患者。肌肉骨骼肿瘤学会评分低与手术时间长（超过 120 分钟）、前间隔肿瘤和两个以上肌肉切除有关。此外，内侧间隔的软组织肉瘤和 III 期肉瘤与 5 年无转移生存率低有关。
内侧间隔的软组织肉瘤与术后黏液肿和转移有关，而前间隔的肉瘤与术后功能低下有关。
