Ivanov V A, Terpilovskaia O N, Kulikov A V, Tret'iak T M
Tsitologiia. 1987 Jan;29(1):73-8.
A study was made of the DNA synthesis in cerebral cortex of rats, aged 14 and 60 days, after gamma-irradiation in vivo in a dose of 7 Gy, the 3H-thymidine incorporation into DNA being determined.137 Cs-radiation induces additional DNA synthesis in the neocortex tissue and in neurons. In the cortex of 14 day-old rats, the induced DNA synthesis stops 2 hours after irradiation, whereas in the cortex of 60 day-old rats and in neurons of rats of both the age groups DNA synthesis is proceeding for 3-3.5 hours. Specificity of DNA reparation processes in non-dividing cells is discussed.
对14日龄和60日龄大鼠进行体内7 Gy剂量的γ射线照射后，研究了其大脑皮层中的DNA合成情况，并测定了3H-胸腺嘧啶核苷掺入DNA的量。137Cs辐射诱导新皮层组织和神经元中额外的DNA合成。在14日龄大鼠的皮层中，诱导的DNA合成在照射后2小时停止，而在60日龄大鼠的皮层以及两个年龄组大鼠的神经元中，DNA合成持续3 - 3.5小时。讨论了非分裂细胞中DNA修复过程的特异性。
