Department of Epidemiology and Biostatistics, School of Public Health, Anhui Medical University, 81 Meishan Road, Hefei, Anhui, China.
Environ Sci Pollut Res Int. 2022 Oct;29(49):74909-74920. doi: 10.1007/s11356-022-21127-8. Epub 2022 Jun 1.
Recently, the high prevalence of hypertension (HTN) has caused serious disease burden. Previous studies mostly focused on the separate association between outdoor or indoor air pollution and HTN, and did not explore their possible interaction with HTN. To explore this issue, this study investigated the relationship between indoor and outdoor air pollution and HTN and their possible interactions among adult residents in 14 rural areas in eastern China. The generalized linear model (GLM) and interplot model were used to evaluate the separate effects and potential interaction of outdoor or indoor air pollutants on HTN. In separate analyses, we found a significant positive association between outdoor and indoor air pollution and HTN, and a significant negative association between range hood use and HTN. In the interaction analysis, outdoor air pollution could significantly enhance the positive effects of indoor air pollution on HTN. In addition, PM and O could significantly reduce the protective effect of range hoods use on HTN. Finally, we found that females were more susceptible to both indoor and outdoor air pollution.
近年来，高血压（HTN）的高发率导致了严重的疾病负担。之前的研究大多集中在室外或室内空气污染与 HTN 的单独关联上，并未探讨它们与 HTN 之间可能存在的相互作用。为了探讨这一问题，本研究在中国东部的 14 个农村地区调查了室内外空气污染与 HTN 之间的关系及其可能的相互作用。使用广义线性模型（GLM）和交互绘图模型评估了室外或室内空气污染物对 HTN 的单独影响和潜在相互作用。在单独分析中，我们发现室外和室内空气污染与 HTN 呈显著正相关，抽油烟机的使用与 HTN 呈显著负相关。在交互分析中，室外空气污染可以显著增强室内空气污染对 HTN 的正向作用。此外，PM 和 O 可以显著降低抽油烟机使用对 HTN 的保护作用。最后，我们发现女性对室内外空气污染更敏感。
