Department of Biology, Allama Iqbal Open University (Main Campus), Sector H-8, Islamabad, Pakistan.
Department of Botany, The Islamia University of Bahawalpur (Baghdad-ul-Jadeed Campus), Bahawalpur, Pakistan.
Pak J Pharm Sci. 2022 Mar;35(2):529-537.
Medicinal plants in most of societies have been a source of quality health care. The indigenous populations are getting many ethnomedicinal products form local biodiversity. The current study aimed to investigate anti-diabetic plants in 8 villages (Patriata, Surasi, Charhan, Lower toppa, Ghikagali, Kashmir point, Pindi point and Shawala) of rural Murree. The methodology included preparation of questionnaire, identification of plants and phytochemical analysis. The informants were asked about vernacular name, part used and folk recipe. The quantitative study included fidelity level, use value and relative frequency of citation of plant species. Data indicated that 30% of patients use local herbs to treat diabetes. The most significant plant species were Berberis lycium with use value of 0.50 followed by Melia azedarach with use value of 0.43 and Himalaiella heteromalla with use value of 0.33. Himalaiella heteromalla was selected for phytochemical analysis. Total flavonoid content was 7.25±0.08mg (ethanol extract) and 6.03±0.13mg (chloroform extract) quercetin equivalent/gm of extract; total phenolic content was 53.92±0.47mg (ethanol extract) and 72.75±0.48mg (chloroform extract) quercetin equivalent/gm of extract; total β-Carotene content was 29.7μg/g in ethanol extract, and 27.26μg/g in chloroform extract while total lycopene content was 46.33μg/g (ethanol extract) and 41.54μg/g (chloroform extract) in H. heteromalla. The results suggest that medicinal plants of Murree region may be potential natural resources for antidiabetic compounds.
在大多数社会中，药用植物一直是优质医疗保健的来源。土著居民从当地生物多样性中获得了许多民族医学产品。本研究旨在调查农村默里的 8 个村庄（Patriata、Surasi、Charhan、Lower toppa、Ghikagali、Kashmir point、Pindi point 和 Shawala）的抗糖尿病植物。方法包括准备问卷、鉴定植物和植物化学分析。询问了当地人植物的俗名、使用部位和民间配方。定量研究包括植物种的保真度水平、使用价值和相对引用频率。数据表明，30%的患者使用当地草药治疗糖尿病。最显著的植物物种是 Berberis lycium，其使用价值为 0.50，其次是 Melia azedarach，使用价值为 0.43，Himalaiella heteromalla，使用价值为 0.33。选择 Himalaiella heteromalla 进行植物化学分析。总黄酮含量为 7.25±0.08mg（乙醇提取物）和 6.03±0.13mg（氯仿提取物）槲皮素当量/gm 提取物；总酚含量为 53.92±0.47mg（乙醇提取物）和 72.75±0.48mg（氯仿提取物）槲皮素当量/gm 提取物；β-胡萝卜素总含量为 29.7μg/g 乙醇提取物，27.26μg/g 氯仿提取物，番茄红素总含量为 46.33μg/g（乙醇提取物）和 41.54μg/g（氯仿提取物）在 H. heteromalla 中。结果表明，默里地区的药用植物可能是抗糖尿病化合物的潜在天然资源。
