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慢性锥虫病对东海岸热免疫接种的影响。

Effect of chronic trypanosomiasis on immunization against East Coast fever.

作者信息

Taracha E L, Irvin A D, Morzaria S P, Moloo S K, Katende J M, Kiarie J N

出版信息

Vet Parasitol. 1986 Dec;22(3-4):215-22. doi: 10.1016/0304-4017(86)90108-1.

DOI:10.1016/0304-4017(86)90108-1
PMID:3564324
Abstract

Two experiments were carried out in which uninfected cattle, or cattle chronically infected with Trypanosoma congolense, were immunized by the infection and treatment method against East Coast fever (ECF; Theileria parva infection). Chronic trypanosomiasis did not prevent cattle mounting an effective immunological response to ECF immunization and resisting subsequent lethal challenge. There appeared to be no difference in the level or quality of immunity between uninfected cattle and trypanosome-infected cattle. Thus, T. congolense infection on its own does not appear to provide a constraint to ECF immunization in the field.

摘要

进行了两项实验,在实验中,未感染的牛或慢性感染刚果锥虫的牛通过感染和治疗方法接种疫苗,以预防东海岸热(ECF;小泰氏梨浆虫感染)。慢性锥虫病并未阻止牛对ECF免疫接种产生有效的免疫反应,也未阻止其抵抗随后的致命攻击。未感染的牛和感染锥虫的牛在免疫水平或质量上似乎没有差异。因此,仅刚果锥虫感染似乎并不会对现场的ECF免疫接种造成限制。

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