开发一种新的预测指数以用于食管闭锁吻合术后吻合口漏：来自单个中心的初步结果。
Developing a new predictive index for anastomotic leak following the anastomosis of esophageal atresia: preliminary results from a single centre.
机构信息
Department of Cardiothoracic Surgery, Fujian Branch of Shanghai Children's Medical Center, Fuzhou City, China.
Fujian Children's Hospital, 966 Hengyu Road, Fuzhou City, Fujian Province, China.
出版信息
J Cardiothorac Surg. 2022 May 28;17(1):131. doi: 10.1186/s13019-022-01878-8.
BACKGROUND
The aim of this study was to determine a predictive index for the risk of anastomotic leak following esophageal atresia anastomosis, METHODS: This article reviewed the clinical data of 74 children with esophageal atresia in Fujian Children's hospital. The risk factors for anastomotic leak were analysed, and a new predictive index was proposed.
RESULTS
The incidence of anastomotic leak was 29.7% after anastomosis in 74 children with esophageal atresia. Birth weight and gap length were risk factors for anastomotic leak. Logistic regression analysis showed that birth weight (Wald 2 = 4.528, P = 0.033, OR = 0.273) was a protective factor for anastomotic leak, whereas gap length (Wald 2 = 7.057, P = 0.008, OR = 2.388) was a risk factor for anastomotic leak. The ratio of gap length to birth weight had a positive predictive effect on the occurrence of anastomotic leak (AUC = 0.732, P = 0.002).
CONCLUSION
Birth weight and gap length are important predictors of anastomotic leak in esophageal atresia. Measurement of the ratio of gap length to birth weight is a helpful predictive index for anastomotic leak following the anastomosis of esophageal atresia.
背景
本研究旨在确定食管闭锁吻合术后吻合口漏的风险预测指标。
方法
本文回顾了福建儿童医院 74 例食管闭锁患儿的临床资料。分析了吻合口漏的危险因素，并提出了一种新的预测指标。
结果
74 例食管闭锁患儿吻合后吻合口漏发生率为 29.7%。出生体重和间隙长度是吻合口漏的危险因素。Logistic 回归分析显示，出生体重（Wald 2=4.528，P=0.033，OR=0.273）是吻合口漏的保护因素，而间隙长度（Wald 2=7.057，P=0.008，OR=2.388）是吻合口漏的危险因素。间隙长度与出生体重的比值对吻合口漏的发生有阳性预测作用（AUC=0.732，P=0.002）。
结论
出生体重和间隙长度是食管闭锁吻合口漏的重要预测因素。测量间隙长度与出生体重的比值是预测食管闭锁吻合后吻合口漏的有用指标。
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