Elbarbary Mohamed M, Shalaby Aly, Elseoudi Mohamed, Seleim Hamed M, Ragab Moutaz, Fares Ahmed E, Khairy Dalia, Wishahy Ahmed M K, Alkonaiesy Ramy M, Eltagy Gamal, Bahaaeldin Khaled
Pediatric Surgical Department, Cairo University Specialized Pediatric Hospital, Cairo, Egypt.
Pediatric Surgical Department, Tanta University Hospital, Tanta, Egypt.
Dis Esophagus. 2020 Feb 12. doi: 10.1093/dote/doaa001.
Thoracoscopic repair of esophageal atresia is gaining popularity worldwide attributable to availability and advances in minimally invasive instruments. In this report, we presented our experience with thoracoscopic esophageal atresia/tracheoesophageal fistula (EA/TEF) repair in our tertiary care institute. A prospective study on short-gap type-C EA/TEF was conducted at Cairo University Specialized Pediatric Hospital between April 2016 and 2018. Excluded were cases with birth weight < 1500 gm, inability to stabilize physiologic parameters, or major cardiac anomalies. The technique was standardized in all cases and was carried out by operating team concerned with minimally invasive surgery at our facility. Primary outcome evaluated was successful primary anastomosis. Secondary outcomes included operative time, conversion rate, anastomotic leakage, recurrent fistula, postoperative stricture, and time till discharge. Over the inclusion period of this study, 136 cases of EA/TEF were admitted at our surgical NICU. Thoracoscopic repair was attempted in 76 cases. In total, 30 cases were pure atresia/long gap type-C atresia and were excluded from the study. Remaining 46 cases met the inclusion criteria and were enrolled in the study. Mean age at operation was 8.7 days (range 2-32), and mean weight was 2.6 Kg (range 1.8-3.6). Apart from five cases (10.8%) converted to thoracotomy, the mean operative time was 108.3 minutes (range 80-122 minute). A tension-free primary anastomosis was possible in all thoracoscopically managed cases (n = 41) cases. Survival rate was 85.4% (n = 35). Anastomotic leakage occurred in seven patients (17%). Conservative management was successful in two cases, while esophagostomy and gastrostomy were judged necessary in the other for five. Anastomotic stricture developed in five cases (16.6%) of the 30 surviving patients who kept their native esophagus. Despite the fact that good mid-term presented results may be due to patient selection bias, thoracoscopic approach proved to be feasible for management of short-gap EA/TEF. Authors of this report believe that thoracoscopy should gain wider acceptance and pediatric surgeons should strive to adopt this procedure.
由于微创器械的可得性及技术进步,胸腔镜下食管闭锁修复术在全球范围内越来越受欢迎。在本报告中,我们介绍了在我们的三级医疗机构进行胸腔镜下食管闭锁/气管食管瘘(EA/TEF)修复术的经验。2016年4月至2018年期间,在开罗大学专科医院对短间隙C型EA/TEF进行了一项前瞻性研究。排除出生体重<1500克、无法稳定生理参数或有重大心脏畸形的病例。所有病例的技术均标准化,由我们机构的微创手术团队进行操作。评估的主要结局是初次吻合成功。次要结局包括手术时间、中转率、吻合口漏、复发性瘘、术后狭窄及出院时间。在本研究的纳入期内,136例EA/TEF患者入住我们的外科新生儿重症监护病房。76例尝试进行胸腔镜修复。总共30例为单纯闭锁/长间隙C型闭锁,被排除在研究之外。其余46例符合纳入标准并纳入研究。平均手术年龄为8.7天(范围2 - 32天),平均体重为2.6千克(范围1.8 - 3.6千克)。除5例(10.8%)中转开胸外,平均手术时间为108.3分钟(范围80 - 122分钟)。所有经胸腔镜治疗的病例(n = 41)均实现了无张力初次吻合。生存率为85.4%(n = 35)。7例患者(17%)发生吻合口漏。2例经保守治疗成功,另外5例则认为需要进行食管造口术和胃造口术。在保留原生食管的30例存活患者中,5例(16.6%)发生吻合口狭窄。尽管中期呈现的良好结果可能归因于患者选择偏倚,但胸腔镜方法被证明对短间隙EA/TEF的治疗是可行的。本报告的作者认为胸腔镜检查应得到更广泛的认可,小儿外科医生应努力采用这一手术方法。