Servicio de Microbiología, Hospital de Pediatría S.A.M.I.C. "Prof. Dr. Juan P. Garrahan" Ciudad Autónoma de Buenos Aires, Argentina.
Servicio de Infectología, Hospital de Pediatría S.A.M.I.C. "Prof. Dr. Juan P. Garrahan" Ciudad Autónoma de Buenos Aires, Argentina.
Rev Argent Microbiol. 2022 Oct-Dec;54(4):318-321. doi: 10.1016/j.ram.2022.02.002. Epub 2022 May 25.
Scedosporium/Lomentospora species are widely distributed in nature. They are generally saprophytes, but can cause opportunistic infections in immunocompromised patients and occasionally in immunocompetent patients that are difficult to treat due to high levels of antifungal resistance. The distribution of Scedosporium/Lomentospora species shows regional differences. Scedosporium boydii and Scedosporium apiospermum are the most frequently isolated species in our region, whereas Scedosporium aurantiacum is more common in other regions. We describe the first isolation in Argentina of S. aurantiacum in a vitreous humor infection from a previously healthy patient after traumatic injury in her left eye. Due to the suspicion of fungal endophthalmitis, a mycological study of the vitreous humor was performed. The culture allowed the isolation of S. aurantiacum. The patient was treated with voriconazole with favorable clinic evolution.
枝顶孢属/节菱孢属广泛分布于自然界。它们通常是腐生菌,但可在免疫功能低下的患者中引起机会性感染,偶尔也可在免疫功能正常的患者中引起感染,这是因为它们对抗真菌药物的耐药性较高,治疗较为困难。枝顶孢属/节菱孢属的分布存在地域差异。在我们地区,最常分离到的种是 Boydii 枝顶孢和 Apiospermum 节菱孢,而在其他地区,更常见的是 Aurantiacum 枝顶孢。我们描述了首例来自阿根廷的病例,一位左眼外伤的既往健康患者发生了玻璃体腔感染,分离出了 Aurantiacum 枝顶孢。由于怀疑真菌性眼内炎,对玻璃体进行了真菌学研究。培养物可分离出 Aurantiacum 枝顶孢。该患者接受了伏立康唑治疗,临床转归良好。