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经皮冠状动脉介入治疗后心脏康复转介的趋势和预测因素:维多利亚心脏结局登记处(2017-2020 年)41739 例患者的前瞻性多中心研究。

Trends and Predictors of Cardiac Rehabilitation Referral Following Percutaneous Coronary Intervention: A Prospective, Multi-Site Study of 41,739 Patients From the Victorian Cardiac Outcomes Registry (2017-2020).

机构信息

School of Public Health and Preventive Medicine, Monash University, Melbourne, Vic, Australia; Department of Cardiology, The Alfred Hospital, Melbourne, Vic, Australia.

School of Public Health and Preventive Medicine, Monash University, Melbourne, Vic, Australia; School of Nursing and Midwifery, Deakin University, Geelong, Vic, Australia; Department of Cardiology, Austin Health, Melbourne, Vic, Australia.

出版信息

Heart Lung Circ. 2022 Sep;31(9):1247-1254. doi: 10.1016/j.hlc.2022.04.050. Epub 2022 May 25.

Abstract

BACKGROUND

Following percutaneous coronary intervention (PCI), outpatient cardiac rehabilitation (CR) is essential for secondary prevention. However uptake of CR is suboptimal, despite strong evidence demonstrating benefits. The aim of this study was to identify contemporary trends and predictors of CR referral of PCI patients in Victoria.

METHODS

A prospective, observational study using data extracted from the Victorian Cardiac Outcomes Registry was undertaken. A total of 41,739 patients were discharged following PCI over the study period (2017-2020) and included for analysis.

RESULTS

Cardiac rehabilitation referral was 85%, with an increasing trend over time (p<0.001). Multivariable modelling identifying the independent predictors of CR referral included hospitals with high volumes of ST-elevation myocardial infarction patients (STEMI) (OR 4.89, 95% CI 4.41-5.20), STEMI diagnosis (OR 1.90, 95% CI 1.69-2.14), or treatment in a private hospital (OR 1.45, 95% CI 1.33-1.57). Predictors of non-referral included cardiogenic shock (OR 0.54, 95% CI 0.41-0.71), aged over 75 years (OR 0.62, 95% CI 0.57-0.68) and previous PCI (OR 0.66, 95% CI 0.62-0.70). Percutaneous coronary intervention patients with an acute coronary syndrome who were referred to CR were also more likely to be prescribed four or more major preventive pharmacotherapies, compared to those who were not referred (90% vs 82.1%, p<0.001).

CONCLUSION

Our contemporary multicentre analysis showed generally high CR referral rates which have increased over time. However, more effort is needed to target patients treated in the public sector, low volume STEMI hospitals or with short lengths of stay.

摘要

背景

经皮冠状动脉介入治疗(PCI)后,门诊心脏康复(CR)是二级预防的关键。然而,尽管有强有力的证据表明 CR 有益,但 CR 的接受度仍不理想。本研究旨在确定维多利亚州 PCI 患者 CR 转介的当代趋势和预测因素。

方法

采用前瞻性、观察性研究,使用从维多利亚心脏结局登记处提取的数据进行分析。在研究期间(2017-2020 年),共有 41739 例患者接受 PCI 治疗后出院,并纳入分析。

结果

CR 转介率为 85%,呈上升趋势(p<0.001)。多变量模型确定 CR 转介的独立预测因素包括 ST 段抬高型心肌梗死(STEMI)患者数量较高的医院(OR 4.89,95%CI 4.41-5.20)、STEMI 诊断(OR 1.90,95%CI 1.69-2.14)或在私立医院治疗(OR 1.45,95%CI 1.33-1.57)。非转介的预测因素包括心源性休克(OR 0.54,95%CI 0.41-0.71)、年龄>75 岁(OR 0.62,95%CI 0.57-0.68)和既往 PCI(OR 0.66,95%CI 0.62-0.70)。被转介至 CR 的急性冠状动脉综合征 PCI 患者更有可能被开四种或更多主要预防药物治疗,而非被转介的患者(90%比 82.1%,p<0.001)。

结论

我们的当代多中心分析显示,CR 转介率总体较高,且呈上升趋势。然而,仍需努力针对在公共部门、低容量 STEMI 医院或住院时间较短的患者进行转介。

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