Altŭnkova I, Bocheva S, Terziivanov D, Belovezhdov N
Vutr Boles. 1986;25(6):35-8.
Lymphocyte subpopulations in peripheral blood were studied in 30 patients with IgA-glomerulonephritis and 24 healthy subjects via application of specific monoclonal antibodies. The following deviations were established: reduced number of OKT11 + cells (37.83 +/- 13.34, p less than 0.01): increased number of OKT8 + cells (25.89 +/- 6.70, p less than 0.01), no change in the number of OKM4 + cells, increased number of peripheral monocytes--OKM1 + cells (19.26 +/- 6.63, p less than 0.001). No significant correlations were established between the deviated parameters and arterial pressure, serum creatinine and serum IgA levels.
通过应用特异性单克隆抗体,对30例IgA肾小球肾炎患者和24名健康受试者的外周血淋巴细胞亚群进行了研究。发现了以下偏差:OKT11 +细胞数量减少(37.83 +/- 13.34,p <0.01);OKT8 +细胞数量增加(25.89 +/- 6.70,p <0.01),OKM4 +细胞数量无变化,外周血单核细胞——OKM1 +细胞数量增加(19.26 +/- 6.63,p <0.001)。在这些偏差参数与动脉血压、血清肌酐和血清IgA水平之间未发现显著相关性。