Petrov D
Vutr Boles. 1986;25(6):66-70.
A total of 203 patients in asthmatic state were studied. Out of the patients studied 98 (48.27%) were in stage I of asthmatic state, 87 (42.85%) in stage II and 18 (8.86%) in stage III. In 7 patients (3.44%), the asthmatic state advanced quickly with generalized bronchospasm. The patients were in hypoxemic coma in the course of several minutes, with a drastic deterioration of the clinical picture, resembling anaphylactic shock. That clinical picture is accepted as anaphylactic form of asthmatic state. According to our studies that form is responsible for 3.44% of all patients in asthmatic state. In addition to the contact with the allergen, some other unspecific irritants--chemical, physical, stress situations, physical loading, etc. are admitted as provoking moments in the development of the anaphylactic form of asthmatic state. Emergency inclusion of adrenaline, high doses of corticosteroids are considered as urgent therapeutic measures in that form of asthmatic state as well as the inclusion of xanthine derivatives in the proper moment and when necessary--artificial pulmonary ventilation.
共对203例处于哮喘状态的患者进行了研究。在这些被研究的患者中，98例（48.27%）处于哮喘状态I期，87例（42.85%）处于II期，18例（8.86%）处于III期。7例患者（3.44%）哮喘状态迅速进展，伴有全身性支气管痉挛。患者在几分钟内陷入低氧性昏迷，临床症状急剧恶化，类似过敏性休克。这种临床症状被认为是哮喘状态的过敏形式。根据我们的研究，这种形式在所有哮喘状态患者中占3.44%。除了接触过敏原外，一些其他非特异性刺激因素——化学、物理、应激情况、体力负荷等——被认为是哮喘状态过敏形式发展过程中的诱发因素。紧急注射肾上腺素、大剂量皮质类固醇被视为这种哮喘状态形式的紧急治疗措施，以及在适当时候并在必要时使用黄嘌呤衍生物——人工肺通气。
