Monov A, Lazarova K, Khubenova A
Vutr Boles. 1986;25(6):77-82.
The authors share their experience in the clinical observation and treatment of 72 children with acute intoxications by tricyclic antidepressants. The syndromes, forming the clinical picture of the acute intoxication at that age were the cerebrotoxic, cholinolytic and cardiotoxic ones. According to their content, the intoxication advanced in three forms: light, moderately severe and severe. The complex application of the therapeutic methods from the unified therapeutic system for the treatment of acute intoxications gave lethality of 5.5%, determined, primarily, by the late admittance of the children for hospital treatment in a state of decompensated phase of exotoxic shock. The anamnestic data for administration of tricyclic preparation in toxic and lethal doses is a signal for hospitalization of the chill with the inclusion of all necessary procedures with a dynamic follow up of its state.
作者分享了他们对72例三环类抗抑郁药急性中毒儿童的临床观察与治疗经验。在该年龄段形成急性中毒临床表现的综合征为脑毒性、抗胆碱能和心脏毒性综合征。根据中毒程度，中毒进展分为三种形式：轻度、中度重度和重度。采用统一治疗系统中治疗急性中毒的治疗方法联合应用，致死率为5.5%，主要原因是患儿在中毒性休克失代偿期才入院接受治疗。服用三环类制剂达到中毒和致死剂量的既往史资料是患儿住院的信号，需纳入所有必要程序并对其病情进行动态随访。
