Covaci Antoanela, Ciocan Lucian Toma, Gălbinașu Bogdan, Bucur Mirela Veronica, Matei Mădălina, Didilescu Andreea Cristiana
Department of Embryology, Faculty of Dental Medicine, "Carol Davila" University of Medicine and Pharmacy, 050474 Bucharest, Romania.
Department of Dental Medicine, Faculty of Medicine and Pharmacy, Dunarea de Jos University of Galati, 800010 Galati, Romania.
J Funct Biomater. 2022 May 2;13(2):51. doi: 10.3390/jfb13020051.
Dental pulp vitality preservation in dental caries treatment is a major goal in odontotherapy. The main objective of this study was to compare dental pulp tissue responses to vital therapies in deep carious lesions, using different calcium-based materials. An ambispective study was conducted on 47 patients. Ninety-five teeth with deep carious lesions were treated. Among them, 25 (26.32%) were diagnosed with pulpal exposures and treated by direct pulp capping. Indirect pulp capping was applied when pulp exposure was absent (n = 70; 73.68%). Fifty teeth (52.63%) were treated with TheraCal LC (prospective study), 31 teeth (32.63%) with Calcimol LC, and 14 teeth (14.74%) with Life Kerr AC (retrospective study). The results show that the survival rate for dental pulp was 100% for Life Kerr AC, 92% for TheraCal LC, and 83.87% for Calcimol LC, without significant differences. Apparently, self-setting calcium hydroxide material provided better dental pulp response than the two light-cured materials, regardless of their composition, that is, either calcium -hydroxide or calcium silicate-based. We will need a significant number of long-term clinical studies with the highest levels of evidence to determine the most adequate biomaterials for vital pulp therapies.
龋病治疗中保存牙髓活力是牙科学治疗的主要目标。本研究的主要目的是比较使用不同钙基材料时，深龋病变中牙髓组织对牙髓活力治疗的反应。对47例患者进行了一项前瞻性和回顾性相结合的研究。对95颗患有深龋病变的牙齿进行了治疗。其中，25颗（26.32%）被诊断为牙髓暴露并接受了直接盖髓治疗。当未出现牙髓暴露时应用间接盖髓术（n = 70；73.68%）。50颗牙齿（52.63%）用TheraCal LC进行治疗（前瞻性研究），31颗牙齿（32.63%）用Calcimol LC治疗，14颗牙齿（14.74%）用Life Kerr AC进行治疗（回顾性研究）。结果显示，Life Kerr AC治疗的牙髓存活率为100%，TheraCal LC为92%，Calcimol LC为83.87%，差异无统计学意义。显然，自凝氢氧化钙材料比两种光固化材料能提供更好的牙髓反应，无论其成分是氢氧化钙还是硅酸钙基。我们需要大量具有最高证据水平的长期临床研究，以确定用于牙髓活力治疗的最合适生物材料。
