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MED-TLIF联合经皮椎弓根螺钉内固定对腰椎滑脱症患者功能及脊柱骨盆参数的影响

Effect of MED-TLIF Combined with Percutaneous Pedicle Screw Fixation on Function and Spinal Pelvic Parameters in Patients with Lumbar Spondylolisthesis.

作者信息

Lv Huiqiang, Bi Hailiang, Wei Jianming, Xia Bin

机构信息

The Second Department of Spine, Baoji Hospital of Traditional Chinese Medicine, Baoji, Shanxi 721001, China.

出版信息

Emerg Med Int. 2022 May 20;2022:2577920. doi: 10.1155/2022/2577920. eCollection 2022.

Abstract

BACKGROUND

Lumbar spondylolisthesis is a common clinical spinal lesion. The upper vertebral body of the patient is displaced relative to the lower vertebral body, causing spinal instability and nerve compression. The clinical manifestations are low back and leg pain, abnormal lower limb sensation, and intermittent rupture. In severe cases, cauda equina syndrome and paraplegia may occur. Minimally invasive spinal surgery has developed rapidly in recent years and become the preferred treatment for lumbar spondylolisthesis.

OBJECTIVE

The aim of this study is to investigate the clinical effect of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) combined with percutaneous pedicle screw fixation in the treatment of lumbar spondylolisthesis under microscope.

METHODS

The clinical and surgical data of 106 patients with lumbar spondylolisthesis treated in our hospital were selected and divided into research group (56 cases) according to surgical methods (MIS-TLIF combined with percutaneous pedicle screw fixation). The other 50 patients were treated with traditional open percutaneous intervertebral foramen fusion (control group). The surgical trauma-related indicators, visual analog pain scale (VAS) scores before and after surgery, modified Japanese Orthopedic Association low back pain score (JOA), bone graft fusion effect, spinal pelvic parameters, and surgical complications of the two groups were statistically analyzed in detail.

RESULTS

The incision length, intraoperative blood loss, operation time, and hospitalization time in the research group were lower than those in the control group, and the differences were statistically significant ( < 0.05). There was no significant difference in the VAS score and JOA score between the two groups before operation ( > 0.05). The VAS score and JOA score of the research group were lower than those of the control group on the first day after operation ( < 0.05). There was no significant difference in the VAS score and JOA score between the two groups at 1 month and 3 months after operation ( > 0.05). Six months, 12 months, and 18 months after operation, the bone graft fusion rates in the research group were 42.86%, 73.21%, and 94.64%, respectively, and those in the control group were 40.00%, 68.00%, and 92.00%, respectively, with no significant difference ( > 0.05). There was no significant difference in PI, PT, SS, LL, TK, LSJA, and SVA between the two groups before and 6 months after operation ( > 0.05). At 6 months after operation, the PT and TK values of the two groups were higher than those before operation ( < 0.05), and the SS, LL, LSJA, and SVA values of the two groups were lower than those before operation ( < 0.05). The complication rate of the research group was 3.57%, which was lower than 18.00% of the control group, and the difference was statistically significant ( < 0.05).

CONCLUSION

MIS-TLIF combined with percutaneous pedicle screw fixation in the treatment of lumbar spondylolisthesis has the same effect as traditional open surgery and has the same correction effect for spinal pelvic parameters, but it has the advantages of less trauma and fewer complications.

摘要

背景

腰椎滑脱是临床常见的脊柱病变。患者上位椎体相对于下位椎体发生移位,导致脊柱不稳和神经受压。临床表现为腰腿痛、下肢感觉异常及间歇性跛行。严重时可出现马尾综合征和截瘫。近年来,微创脊柱手术发展迅速,已成为腰椎滑脱的首选治疗方法。

目的

本研究旨在探讨显微镜下微创经椎间孔腰椎椎体间融合术(MIS-TLIF)联合经皮椎弓根螺钉内固定治疗腰椎滑脱的临床效果。

方法

选取我院收治的106例腰椎滑脱患者的临床及手术资料,根据手术方式分为研究组(56例,采用MIS-TLIF联合经皮椎弓根螺钉内固定),另50例采用传统开放经椎间孔融合术治疗为对照组。详细统计分析两组手术创伤相关指标、手术前后视觉模拟疼痛评分(VAS)、改良日本骨科学会腰痛评分(JOA)、植骨融合效果、脊柱骨盆参数及手术并发症。

结果

研究组切口长度、术中出血量、手术时间及住院时间均低于对照组,差异有统计学意义(P<0.05)。两组术前VAS评分及JOA评分比较,差异无统计学意义(P>0.05)。研究组术后第1天VAS评分及JOA评分低于对照组,差异有统计学意义(P<0.05)。两组术后1个月及3个月VAS评分及JOA评分比较,差异无统计学意义(P>0.05)。术后6个月、12个月及18个月,研究组植骨融合率分别为42.86%、73.21%、94.64%,对照组分别为40.00%、68.00%、92.00%,差异无统计学意义(P>0.05)。两组术前及术后6个月矢状面垂直轴(PI)、骨盆入射角(PT)、骶骨倾斜角(SS)、腰椎前凸角(LL)、胸椎后凸角(TK)、腰椎滑脱角(LSJA)及矢状面轴向垂直距离(SVA)比较,差异无统计学意义(P>0.05)。术后6个月,两组PT及TK值高于术前(P<0.05),SS、LL、LSJA及SVA值低于术前(P<0.05)。研究组并发症发生率为3.57%,低于对照组的18.00%,差异有统计学意义(P<0.05)。

结论

MIS-TLIF联合经皮椎弓根螺钉内固定治疗腰椎滑脱与传统开放手术效果相同,对脊柱骨盆参数的矫正效果相同,但具有创伤小、并发症少的优点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3380/9142272/7595a8f471e4/EMI2022-2577920.001.jpg

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