Palm L, Blennow G, Brun A
Acta Paediatr Scand. 1986 Sep;75(5):855-9. doi: 10.1111/j.1651-2227.1986.tb10302.x.
Six infants with infantile spasms are presented, three primarily considered idiopathic and three symptomatic. Autopsy unexpectedly revealed heterotopias, cortical dyslamination, and other brain malformations in all six cases. No history of any etiologic moment during the neuronal migratory period of early gestation was found. It is concluded that wide-spread disturbances of CNS morphology should always be considered in cases of infantile spasms.
本文报告了6例婴儿痉挛症患儿，其中3例初步诊断为特发性，3例为症状性。尸检意外发现所有6例均有异位、皮质发育异常及其他脑畸形。未发现孕早期神经元迁移期有任何病因学相关病史。结论是，婴儿痉挛症病例应始终考虑存在广泛的中枢神经系统形态学紊乱。
