Nielsen O G, Pilgaard P
Acta Paediatr Scand. 1987 Jan;76(1):133-6. doi: 10.1111/j.1651-2227.1987.tb10429.x.
Familial accumulation of spinal osteochondrosis (Scheuermann's disease) and hereditary juvenile anterior fusion of the vertebral bodies in the thoraco-lumbal area are reported for the first time in the same family. Radiological examination of the spine in 2 planes of 73 persons formed the basis for the study. Nine cases of spinal osteochondrosis and 5 cases of hereditary juvenile anterior fusion were found. Proliferation and increased height of the anterior surface of the body of the vertebrae and pronounced reduction in the anterior aspect of the intervertebral spaces were characteristic during the early stages of the latter condition, similarly fewer back symptoms and a better prognosis were observed in these patients than was the case of patients with Scheuermann's disease.
首次报道了在同一家庭中出现脊柱骨软骨病（休曼氏病）的家族聚集现象以及胸腰段椎体的遗传性青少年前路融合。对73人的脊柱进行两个平面的放射学检查构成了本研究的基础。发现9例脊柱骨软骨病和5例遗传性青少年前路融合。在后者疾病的早期阶段，椎体前缘增殖和高度增加以及椎间隙前缘明显变窄是其特征，同样，这些患者的背部症状较少，预后也比休曼氏病患者更好。
