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视神经切断后金鱼视网膜神经元早期退变模式。

Early patterns of neuronal degeneration in the retina of the goldfish after optic nerve sectioning.

作者信息

Yew D T, Li W W

出版信息

Acta Morphol Neerl Scand. 1986;24(2):123-32.

PMID:3565093
Abstract

The early patterns of retinal degeneration were studied in the goldfish after optic nerve sectioning by l.m. and e.m. Beginning on the 2nd postsurgical day there was an initial degeneration of neurons in the ganglion cell and inner nuclear layers of the central retina. Massive ganglion cell degeneration in the whole retina (60%) as well as degeneration of neurons in inner and outer nuclear layer of the peripheral retina was evident around the 7th postsurgical day. The early degenerating cells appeared to be cones and cone bipolars.

摘要

通过光镜和电镜研究了金鱼视神经切断术后视网膜变性的早期模式。术后第2天开始,中央视网膜神经节细胞层和内核层的神经元出现最初的变性。术后第7天左右,整个视网膜出现大量神经节细胞变性(60%),周边视网膜内核层和外核层的神经元也出现变性。早期退化的细胞似乎是视锥细胞和视锥双极细胞。

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