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发酵食品:基于证据的健康益处的最新更新和未来展望。

Fermented foods: An update on evidence-based health benefits and future perspectives.

机构信息

Departamento de Química Aplicada, Facultad de Químicas, Universidad del País Vasco (UPV/EHU), 20018 San Sebastián, Spain; Departamento de Biotecnología Microbiana y de Plantas, Centro de Investigaciones Biológicas Margarita Salas (CIB, CSIC), 28040 Madrid, Spain.

Osakidetza, University Hospital of Álava (HUA), José Atxotegi Kalea s/n, 01009 Vitoria-Gasteiz, Spain.

出版信息

Food Res Int. 2022 Jun;156:111133. doi: 10.1016/j.foodres.2022.111133. Epub 2022 Mar 15.

Abstract

In recent years, an unstoppable trend toward minimally processed foods has increased the popularity of fermented foods as a beneficial nutritional and functional strategy. Within food fermentations, complex microbial communities trigger different biochemical reactions that result in the release of multiple bioactive compounds with beneficial effects on human health. In the present review the latest studies on fermented foods are summarized. Special attention has been paid on the health benefits of main fermented foods available nowadays, the principal bioactive compounds responsible for such properties as well as the future trends of research studies regarding their potentialities. This review emphasizes the need of clinical evidence to ensure that fermented foods may entail a significant improvement on well-being. Fermented foods may represent a non-invasive strategy to face multiple disorders, as hypertension, diabetes, hyperlipidemia, oxidative stress and multiple cognitive disordes, among others. Release of bioactive compounds, microbial enzymatic conversions or probiotic activities are the main responsible for such interesting properties. However, the need of well-designed clinical trials is a must in order to obtain conclusive results. Bioavailability and biodisponibility of bioactive compounds as well as the design of precision probiotics are also another focus of interest in which it must be deepen.

摘要

近年来,人们对低加工食品的需求不断增长,这使得发酵食品作为一种有益的营养和功能性策略越来越受欢迎。在食品发酵过程中,复杂的微生物群落引发不同的生化反应,导致多种具有有益健康作用的生物活性化合物的释放。本综述总结了最新的发酵食品研究。特别关注了目前可获得的主要发酵食品的健康益处、负责这些特性的主要生物活性化合物,以及针对其潜力的未来研究趋势。本综述强调需要临床证据来确保发酵食品可以显著改善健康状况。发酵食品可能是一种非侵入性的策略,可以应对多种疾病,如高血压、糖尿病、高血脂、氧化应激和多种认知障碍等。生物活性化合物的释放、微生物酶转化或益生菌活性是这些特性的主要原因。然而,为了获得确凿的结果,必须进行精心设计的临床试验。生物活性化合物的生物利用度和生物可利用度以及精准益生菌的设计也是另一个关注的焦点,必须对此进行深入研究。

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