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冻疮和早期 SARS-CoV-2 变体:前瞻性队列的自然史和干扰素的作用。

Pernio and early SARS-CoV-2 variants: natural history of a prospective cohort and the role of interferon.

机构信息

Department of Dermatology, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.

Division of Allergy & Immunology, Department of Pediatrics, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA.

出版信息

Br J Dermatol. 2022 Oct;187(4):617-619. doi: 10.1111/bjd.21693. Epub 2022 Jul 6.

DOI:10.1111/bjd.21693
PMID:35653263
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9347790/
Abstract

Cases of new-onset pernio and recurrences in our cohort align tightly with trends in mean 7-day COVID-19 positivity in Wisconsin and mean temperature in Madison, Wisconsin by month.

摘要

在我们的队列中,新发冻疮和复发的病例与威斯康星州 7 天内 COVID-19 阳性率的平均趋势以及威斯康星州麦迪逊市每月的平均温度紧密相关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/229a/9347790/fd118c53383c/BJD-9999-0-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/229a/9347790/fd118c53383c/BJD-9999-0-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/229a/9347790/fd118c53383c/BJD-9999-0-g002.jpg

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本文引用的文献

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Lack of association between pandemic chilblains and SARS-CoV-2 infection.大流行性寒冷性红斑与 SARS-CoV-2 感染之间缺乏关联。
Proc Natl Acad Sci U S A. 2022 Mar 1;119(9). doi: 10.1073/pnas.2122090119.
2
Milder disease with Omicron: is it the virus or the pre-existing immunity?奥密克戎致病较轻:是病毒还是预先存在的免疫力?
Nat Rev Immunol. 2022 Feb;22(2):69-71. doi: 10.1038/s41577-022-00678-4.
3
Type I interferon response and vascular alteration in chilblain-like lesions during the COVID-19 outbreak.COVID-19 疫情期间冻疮样皮损中的 I 型干扰素反应和血管改变。
Br J Dermatol. 2021 Dec;185(6):1176-1185. doi: 10.1111/bjd.20707. Epub 2021 Oct 5.
4
Frequency of relapse and persistent cutaneous symptoms after a first episode of chilblain-like lesion during the COVID-19 pandemic.COVID-19大流行期间冻疮样病变首次发作后复发频率及持续性皮肤症状
J Eur Acad Dermatol Venereol. 2021 Sep;35(9):e566-e568. doi: 10.1111/jdv.17393. Epub 2021 Jun 19.
5
Cold and COVID: recurrent pernio during the COVID-19 pandemic.感冒与新冠:新冠疫情期间的复发性冻疮
Br J Dermatol. 2021 Jul;185(1):214-216. doi: 10.1111/bjd.19894. Epub 2021 Apr 18.
6
Clinical, Laboratory, and Interferon-Alpha Response Characteristics of Patients With Chilblain-like Lesions During the COVID-19 Pandemic.COVID-19 大流行期间冻疮样皮损患者的临床、实验室和干扰素-α反应特征。
JAMA Dermatol. 2021 Feb 1;157(2):202-206. doi: 10.1001/jamadermatol.2020.4324.
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