From the Division of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, Columbia University Irving Medical Center, New York, NY.
the Division of Digestive and Liver Diseases, Department of Medicine, Columbia University Irving Medical Center.
J Pediatr Gastroenterol Nutr. 2022 Sep 1;75(3):231-236. doi: 10.1097/MPG.0000000000003503. Epub 2022 Aug 9.
Esophageal achalasia is a relatively rare disease in children that has been treated with balloon dilatation, botulinum toxin injection, and Heller myotomy. Peroral endoscopic myotomy (POEM) is another treatment that has been successfully employed to treat adults with achalasia for over a decade and has been increasingly used in children. This State of the Art Review from the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition Endoscopy Committee reviews the current literature in pediatric POEM including the technique, success rate, complications as well as training guidelines. Though there is limited data, POEM in children has shown encouraging success rates and with further study may become the mainstay of pediatric achalasia treatment.
食管失弛缓症在儿童中较为罕见，其治疗方法包括球囊扩张、肉毒杆菌毒素注射和 Heller 肌切开术。经口内镜肌切开术（POEM）是另一种治疗方法，十多年来已成功用于治疗成人失弛缓症，并且在儿童中越来越多地使用。北美儿科学胃肠病学、肝病和营养内镜委员会的这篇最新技术综述回顾了儿科 POEM 的现有文献，包括技术、成功率、并发症以及培训指南。虽然数据有限，但儿童 POEM 显示出令人鼓舞的成功率，随着进一步的研究，它可能成为儿童失弛缓症治疗的主要方法。
